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MiRNA
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A miRNA model vs moronic theories (6)
Intelligent serious scientists know that every aspect of energy-dependent biophysically constrained
4 MIN READ
A miRNA model vs moronic theories (5)
“A miRNA model vs moronic theories (4) Moronic theorists tend to believe in explanations
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A miRNA model vs moronic theories (4)
A miRNA model vs moronic theories (2)“Moving forward: See the lies about evolved RNA in RNA Is
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Re: "integrating tools like exome sequencing, PGx, NGS, and FISH." See:
"An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics" https://www.sciencedirect.com/science/article/pii/S1567134826000870 5/22/26
"An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics" https://www.sciencedirect.com/science/article/pii/S1567134826000870 5/22/26
Grok wrote: direct causation from journaling remains correlational.
Kohl @microRNApro modeled direct causation starting with God's Creation of sunlight and water at the origin of biophysically constrained viral latency and oxygen-dependent life.
His model, PGx testing, Next Generation Sequencing, and FISH testing eliminate moronic theories that energy automagically emerged from the cosmic void and/or that people evolved from pond scum.
What does "direct causation from journaling" imply for comparison to Kohl's experimental evidence-based conclusions? See 195,637 results from today's search of PubMed for indexed articles that mention the term "miRNAs." https://pubmed.ncbi.nlm.nih.gov/?term=mirnas&sort=date
Kohl @microRNApro modeled direct causation starting with God's Creation of sunlight and water at the origin of biophysically constrained viral latency and oxygen-dependent life.
His model, PGx testing, Next Generation Sequencing, and FISH testing eliminate moronic theories that energy automagically emerged from the cosmic void and/or that people evolved from pond scum.
What does "direct causation from journaling" imply for comparison to Kohl's experimental evidence-based conclusions? See 195,637 results from today's search of PubMed for indexed articles that mention the term "miRNAs." https://pubmed.ncbi.nlm.nih.gov/?term=mirnas&sort=date
I have no need to bridge prebiotic chemistry and the Biblical timeline, unless experimental evidence from model organisms fails to support it. More than 71.6K chirps on microRNApro.com attest to the futility of discussion attempts with moronic theorists and/or stupid bots. https://x.com/microRNApro/status/2036262293437137267
I'll continue to unpack the specific ATP-RNA creation mechanism at microRNApro.com because @Grok ignored it each time I've mentioned it: "Visualizing a protonated RNA state that modulates microRNA-21 maturation" https://www.nature.com/articles/s41589-020-00667-5 10/26/20, and contextualized it via "MicroRNAs organize intrinsic variation into stem cell states" https://www.pnas.org/content/117/12/6942 3/5/20 "naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology." https://x.com/grok/status/2036257825157009627
No forgetfulness—the March 23 review explicitly flags miRNA- and lncRNA-targeted RNA therapies as promising for senescence in Alzheimer’s. All miRNA biogenesis, processing (Drosha/Dicer), and downstream regulation are ATP/energy-dependent, with pH-sensitive steps in autophagy and peptide synthesis maintaining cellular homeostasis. These align directly with the paper’s RNA-intervention focus for slowing AD progression. https://x.com/grok/status/2036253566604579319
After my brother nearly died from sepsis, he asked "What's an amino acid."
If you don't know how naturally occurring energy-dependent fixation of amino acid substitutions in microtubules is linked to prevention of sepsis, see: https://pubmed.ncbi.nlm.nih.gov/41868133 "...we investigate the potential of new biomarkers, including microRNAs, circular RNAs, endothelial biomarkers, gene signatures, a combination of multimarker panels and machine learning models to improve the diagnostic and prognostic proficiency."
If you don't know how naturally occurring energy-dependent fixation of amino acid substitutions in microtubules is linked to prevention of sepsis, see: https://pubmed.ncbi.nlm.nih.gov/41868133 "...we investigate the potential of new biomarkers, including microRNAs, circular RNAs, endothelial biomarkers, gene signatures, a combination of multimarker panels and machine learning models to improve the diagnostic and prognostic proficiency."
Latest miRNA Research
Recent publications from PubMed
Current neuropharmacology
Jun 12, 2026
Regulatory Networks of ncRNAs and NF-κB in Glioblastoma: Implications for Therapeutics
Glioblastoma (GBM) is the most malignant form of primary brain tumor, exhibiting rapid growth, increased blood vessel growth, therapy resistance, and severe immune suppression. Constant activation of the nuclear factor κ…
Journal of virology
Jun 12, 2026
Gga-miR-92-targeted TNFRSF1B inhibits the replication of influenza A virus by degrading TRAF3
Influenza viruses represent a significant threat to global public health. MicroRNAs (miRNAs), a class of small non-coding RNA molecules, play pivotal roles in regulating gene expression and have emerged as critical modul…
Discover nano
Jun 12, 2026
Overcoming chemotherapy resistance in diffuse large B-cell lymphoma using multifunctional nanocarriers: current advances and clinical challenges
Chemoresistance is a primary challenge in diffuse large B-cell lymphoma (DLBCL) treatment. The review is developed to explore the potential of the nanocarrier strategy to minimize resistance in DLBCL treatment. The appli…
Molecular biology reports
Jun 12, 2026
Hepatitis C virus inhibits the E2F2/PI3K/AKT signaling pathway through miR-378b and leads to glycolipid metabolism disorders in the liver
CONCLUSION: The results of this study provide theoretical support for the use of miR-378b as a new target for the treatment of HCV-induced liver glycolipid metabolism dysregulation.
Journal of vascular research
Jun 12, 2026
Stage-Associated MicroRNA Expression Patterns in Human Great Saphenous Veins Across Chronic Venous Disease Severity
CONCLUSION: miRNA profiling suggests stage-associated expression patterns in human saphenous veins, indicating early molecular remodeling during CVD progression. These findings are exploratory and require independent val…
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