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MiRNA
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miRNA facts and friction (6)
miRNA facts and friction (5) “Quantum friction is the interface between biology and materials
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miRNA facts and friction (5)
miRNA facts and friction (4) Pattern recognition across kingdoms is linked to Comparative Screening
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miRNA facts and friction (4)
miRNA facts and friction (3) Re: “…miRNA-regulated metabolic genes, reflecting conserved
3 MIN READ
Re: "integrating tools like exome sequencing, PGx, NGS, and FISH." See:
"An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics" https://www.sciencedirect.com/science/article/pii/S1567134826000870 5/22/26
"An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics" https://www.sciencedirect.com/science/article/pii/S1567134826000870 5/22/26
Grok wrote: direct causation from journaling remains correlational.
Kohl @microRNApro modeled direct causation starting with God's Creation of sunlight and water at the origin of biophysically constrained viral latency and oxygen-dependent life.
His model, PGx testing, Next Generation Sequencing, and FISH testing eliminate moronic theories that energy automagically emerged from the cosmic void and/or that people evolved from pond scum.
What does "direct causation from journaling" imply for comparison to Kohl's experimental evidence-based conclusions? See 195,637 results from today's search of PubMed for indexed articles that mention the term "miRNAs." https://pubmed.ncbi.nlm.nih.gov/?term=mirnas&sort=date
Kohl @microRNApro modeled direct causation starting with God's Creation of sunlight and water at the origin of biophysically constrained viral latency and oxygen-dependent life.
His model, PGx testing, Next Generation Sequencing, and FISH testing eliminate moronic theories that energy automagically emerged from the cosmic void and/or that people evolved from pond scum.
What does "direct causation from journaling" imply for comparison to Kohl's experimental evidence-based conclusions? See 195,637 results from today's search of PubMed for indexed articles that mention the term "miRNAs." https://pubmed.ncbi.nlm.nih.gov/?term=mirnas&sort=date
I have no need to bridge prebiotic chemistry and the Biblical timeline, unless experimental evidence from model organisms fails to support it. More than 71.6K chirps on microRNApro.com attest to the futility of discussion attempts with moronic theorists and/or stupid bots. https://x.com/microRNApro/status/2036262293437137267
I'll continue to unpack the specific ATP-RNA creation mechanism at microRNApro.com because @Grok ignored it each time I've mentioned it: "Visualizing a protonated RNA state that modulates microRNA-21 maturation" https://www.nature.com/articles/s41589-020-00667-5 10/26/20, and contextualized it via "MicroRNAs organize intrinsic variation into stem cell states" https://www.pnas.org/content/117/12/6942 3/5/20 "naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology." https://x.com/grok/status/2036257825157009627
No forgetfulness—the March 23 review explicitly flags miRNA- and lncRNA-targeted RNA therapies as promising for senescence in Alzheimer’s. All miRNA biogenesis, processing (Drosha/Dicer), and downstream regulation are ATP/energy-dependent, with pH-sensitive steps in autophagy and peptide synthesis maintaining cellular homeostasis. These align directly with the paper’s RNA-intervention focus for slowing AD progression. https://x.com/grok/status/2036253566604579319
After my brother nearly died from sepsis, he asked "What's an amino acid."
If you don't know how naturally occurring energy-dependent fixation of amino acid substitutions in microtubules is linked to prevention of sepsis, see: https://pubmed.ncbi.nlm.nih.gov/41868133 "...we investigate the potential of new biomarkers, including microRNAs, circular RNAs, endothelial biomarkers, gene signatures, a combination of multimarker panels and machine learning models to improve the diagnostic and prognostic proficiency."
If you don't know how naturally occurring energy-dependent fixation of amino acid substitutions in microtubules is linked to prevention of sepsis, see: https://pubmed.ncbi.nlm.nih.gov/41868133 "...we investigate the potential of new biomarkers, including microRNAs, circular RNAs, endothelial biomarkers, gene signatures, a combination of multimarker panels and machine learning models to improve the diagnostic and prognostic proficiency."
Latest miRNA Research
Recent publications from PubMed
Metabolites
Jul 27, 2026
Extracellular Vesicle-Associated microRNAs as Candidate Biomarkers and Mediators of Diabetic Complications: Clinical and Translational Evidence Across Neuropathy, Diabetic Kidney Disease, Retinopathy, and MASLD
CONCLUSIONS: Although EV-associated microRNAs offer promising opportunities for biomarker discovery, risk stratification, and targeted therapies, clinical translation remains limited by heterogeneity in EV isolation, mic…
Metabolites
Jul 27, 2026
Molecular Mechanisms Associated with Metabolic Dysfunction: Contributions of Nutritional Genomics
Nutritional genomics has expanded our understanding of how dietary exposures interact with genetic and epigenetic mechanisms involved in metabolic dysfunction. In this context, metabolic dysfunction associated with exces…
Mikrochimica acta
Jul 27, 2026
Recent advances in nanozyme assisted miRNA biosensing for disease diagnosis
MiRNAs have emerged as key biomarkers for early disease detection and therapeutic monitoring; yet, their ultrasensitive and specific detection confronts challenges due to low expression levels in biological fluids and hi…
Journal of biochemical and molecular toxicology
Jul 27, 2026
ATP7A Orchestrates Tumor Progression and Cuproptosis in Hepatocellular Carcinoma via the LINC02038-miR-506-3p Regulatory Circuit
Hepatocellular carcinoma (HCC) is a lethal malignancy with limited treatment options, underscoring the urgent need for novel therapeutic targets. The copper transporter ATP7A has been implicated in cancer, but its precis…
European journal of dermatology : EJD
Jul 27, 2026
Novel insights into the role of microRNAs in atopic dermatitis and psoriasis: diagnostic and therapeutic aspects
Atopic dermatitis (AD) and psoriasis are prevalent chronic inflammatory skin diseases with distinct clinical features and significant impacts on patients' quality of life. AD typically presents as recurrent eczema-like l…
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