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MiRNA
Researching and documenting to spread the truth!
miRNA processes of gene expression (1)
miRNA abundance prevents virus-driven diseases (10) The [energy-dependent miRNA-mediated] process of
4 MIN READ
miRNA abundance prevents virus-driven diseases (10)
miRNA abundance prevents virus-driven diseases (9) Kohl, whose work centers on miRNA-mediated
4 MIN READ
miRNA abundance prevents virus-driven diseases (9)
miRNA abundance prevents virus-driven diseases (8) Re: Connections from single-molecule tracking or
3 MIN READ
Re: "integrating tools like exome sequencing, PGx, NGS, and FISH." See:
"An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics" https://www.sciencedirect.com/science/article/pii/S1567134826000870 5/22/26
"An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics" https://www.sciencedirect.com/science/article/pii/S1567134826000870 5/22/26
Grok wrote: direct causation from journaling remains correlational.
Kohl @microRNApro modeled direct causation starting with God's Creation of sunlight and water at the origin of biophysically constrained viral latency and oxygen-dependent life.
His model, PGx testing, Next Generation Sequencing, and FISH testing eliminate moronic theories that energy automagically emerged from the cosmic void and/or that people evolved from pond scum.
What does "direct causation from journaling" imply for comparison to Kohl's experimental evidence-based conclusions? See 195,637 results from today's search of PubMed for indexed articles that mention the term "miRNAs." https://pubmed.ncbi.nlm.nih.gov/?term=mirnas&sort=date
Kohl @microRNApro modeled direct causation starting with God's Creation of sunlight and water at the origin of biophysically constrained viral latency and oxygen-dependent life.
His model, PGx testing, Next Generation Sequencing, and FISH testing eliminate moronic theories that energy automagically emerged from the cosmic void and/or that people evolved from pond scum.
What does "direct causation from journaling" imply for comparison to Kohl's experimental evidence-based conclusions? See 195,637 results from today's search of PubMed for indexed articles that mention the term "miRNAs." https://pubmed.ncbi.nlm.nih.gov/?term=mirnas&sort=date
I have no need to bridge prebiotic chemistry and the Biblical timeline, unless experimental evidence from model organisms fails to support it. More than 71.6K chirps on microRNApro.com attest to the futility of discussion attempts with moronic theorists and/or stupid bots. https://x.com/microRNApro/status/2036262293437137267
I'll continue to unpack the specific ATP-RNA creation mechanism at microRNApro.com because @Grok ignored it each time I've mentioned it: "Visualizing a protonated RNA state that modulates microRNA-21 maturation" https://www.nature.com/articles/s41589-020-00667-5 10/26/20, and contextualized it via "MicroRNAs organize intrinsic variation into stem cell states" https://www.pnas.org/content/117/12/6942 3/5/20 "naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology." https://x.com/grok/status/2036257825157009627
No forgetfulness—the March 23 review explicitly flags miRNA- and lncRNA-targeted RNA therapies as promising for senescence in Alzheimer’s. All miRNA biogenesis, processing (Drosha/Dicer), and downstream regulation are ATP/energy-dependent, with pH-sensitive steps in autophagy and peptide synthesis maintaining cellular homeostasis. These align directly with the paper’s RNA-intervention focus for slowing AD progression. https://x.com/grok/status/2036253566604579319
After my brother nearly died from sepsis, he asked "What's an amino acid."
If you don't know how naturally occurring energy-dependent fixation of amino acid substitutions in microtubules is linked to prevention of sepsis, see: https://pubmed.ncbi.nlm.nih.gov/41868133 "...we investigate the potential of new biomarkers, including microRNAs, circular RNAs, endothelial biomarkers, gene signatures, a combination of multimarker panels and machine learning models to improve the diagnostic and prognostic proficiency."
If you don't know how naturally occurring energy-dependent fixation of amino acid substitutions in microtubules is linked to prevention of sepsis, see: https://pubmed.ncbi.nlm.nih.gov/41868133 "...we investigate the potential of new biomarkers, including microRNAs, circular RNAs, endothelial biomarkers, gene signatures, a combination of multimarker panels and machine learning models to improve the diagnostic and prognostic proficiency."
Latest miRNA Research
Recent publications from PubMed
Journal of cardiovascular translational research
Oct 26, 2026
Admission Circulating microRNAs and Residual Congestion in Very Elderly Patients With Acute Decompensated Heart Failure: Associations With miR-223-3p and miR-423-5p
MicroRNAs may provide information about decongestion in acute decompensated heart failure (ADHF). We examined associations with residual congestion and diuretic treatment intensity. In 145 adults with ADHF, seven admissi…
In vitro cellular & developmental biology. Animal
Oct 26, 2026
miR-125b-5p alleviates sepsis-associated acute lung injury by targeting PTP1B to inhibit the endoplasmic reticulum stress-pyroptosis axis
Sepsis-associated acute lung injury (SALI) is a severe complication of sepsis with high mortality, and the molecular mechanisms underlying its pathogenesis remain incompletely elucidated. This study aimed to investigate …
ACS sensors
Oct 26, 2026
CRISPR/Cas13a-Regulated SERS Biosensor Based on Plasmonic-Enhanced Magnetic Rods with Intensified Electromagnetic Field Generation for Breast Cancer Associated miRNA Detection
Early and sensitive detection of breast cancer biomarkers is essential for improving patient prognosis, yet rapid and amplification-free analysis of low-abundance circulating miRNAs remains challenging. Herein, we report…
Proceedings of the National Academy of Sciences of the United States of America
Oct 26, 2026
circEPSTI1 regulates miR-942-5p-SERPINE1-AKT1 signaling axis to enhance dengue infection and is suppressed by Tiplaxtinin
Circular RNAs (circRNAs) have recently been identified as crucial regulators of gene expression in various diseases. Their role in dengue remains unexplored. In this study, circEPSTI1 induction was observed in peripheral…
Briefings in bioinformatics
Oct 26, 2026
Robust and comprehensive meta-path modeling with multi-graph learning for miRNA-disease association prediction
MicroRNA (miRNA)-disease association prediction is important for biomarker discovery and therapeutic target prioritization. However, existing methods have not adequately captured heterogeneous biological semantics while …
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