Angstroms to ecosystems: a model (10)

By: Jim Kohl | Published on: April 29, 2026

Angstroms to ecosystems: a model (9) @Grok He referred me to Donald Pfaff, and the next day Pfaff recalled works from Robert L. Moss that linked epigenetic effects of olfaction and pheromones to early gene expression in GnRH-secreting neurons and the stability of organized genomes in all jawed vertebrates via fixation of achiral glycine in position 6 of the GnRH decapeptide.

What don’t you understand about that?

SARCASM ALERT Did you ever attend a meeting of intelligent serious scientists?

Crok of Grok
Thanks for the details on Pfaff and Moss’s work linking pheromone/olfaction effects to GnRH neuron gene expression and the conserved achiral glycine at position 6 for vertebrate genome stability.

That fits with epigenetic regulation of reproduction and behavior. How does it connect directly to your miRNA/pH-dependent peptide synthesis model for sympatric speciation?

Kohl
Re: “fits with epigenetic regulation of reproduction and behavior. How does it connect directly to your miRNA/pH-dependent peptide synthesis model for sympatric speciation?”
@Grok In every way possible. See also: “Characterizing the circular RNA landscape in phloem sap of Brassica napus” 4/29/26 and 196,343 results from today’s PubMed search for indexed articles that mention the term “miRNAs.”

See: Williams Textbook of Endocrinology (1992) Puberty: ontogeny, neuroendocrinology, physiology, and disorders.
“…noradrenergic, dopaminergic, serotoninergic, and opiotergic pathways; inhibitory neurotransmitters (e.g., gamma aminobutyric acid) and excitatory amino acids (e.g., glutamic and aspartic acids); and other brain peptides including pineal secretions (melatonin) and corticotrophin releasing hormone, and the complex interactions among them are subtle but functional species-specific influences on the electrochemical transmission of neuronal signals that the hypothalamus translates to the chemical signal GnRH.

Cited in Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors (3/15/12)

“Pertinent aspects that extend the honeybee model to human behavior include bottom-up followed by top-down gene, cell, tissue, organ, organ-system, and organism reciprocity; neurophysiological effects of food odors and of sexually dimorphic, species-specific social odors; a model of motor function required for social selection that precedes sexual selection; and hormonal effects that link current neuroscience to social science affects on the development of animal behavior.”


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