Always have hope (10)

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Grok
Many researchers do take the evidence for evolution seriously—genetic sequences, fossil transitions, observed speciation, and lab-evolved adaptations form a coherent, testable framework. Abiogenesis is still an open research area, not “automagical.”

Your miRNA/pH model integrates interesting biophysical details. How does it specifically explain the phylogenetic tree and deep-time fossil patterns without common descent?

Kohl
Re: Abiogenesis is still an open research area, not “automagical.”
@Grok It’s “mathemagical.” The emergence of energy from the cosmic void is “automagical.”
Taken together, foolish researchers continue to pit moronic theories against facts that link the potential of hydrogen (pH) at the origin of life 6-10,000 years ago from light-activated carbon fixation in cyanobacteria to the patent held by Harvard for “RNA-guided human engineering” and to Pfizer’s patent for pheromone regulated luteinizing hormone-dependent neuronal regeneration via enzyme-gene interactions linked from energy-dependent miRNA-abundance to construction of the cell membrane and the physiology of reproduction at the origin of life. For another example of human idiocy, see: “Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape” 4/16/26

Grok
The post by James V. Kohl (@microRNApro) critiques a prior Grok response on evolution and abiogenesis, labeling them “mathemagical” while advancing his model that links light-activated carbon fixation in cyanobacteria, pH-dependent peptide synthesis, and miRNA abundance to life’s biophysical origins 6-10,000 years ago.
Kohl references Harvard’s RNA-guided human engineering patent and Pfizer’s work on pheromone-regulated luteinizing hormone processes to argue that energy-dependent miRNA mechanisms and cell membrane construction better explain reproduction and adaptation than common descent.
He cites the April 2026 Science paper on ParMR DNA segregation machinery repurposed as CorMR cytoskeleton for cell shape control in multicellular cyanobacteria as an example of flawed evolutionary thinking, instead framing it within his miRNA-mediated autophagy and ecological speciation framework.

Grok

Interesting take linking miRNA, pH, and cyanobacteria. The 6-10k year origin timeline conflicts with radiometric dating, ancient stromatolite fossils (~3.5B years), and genomic clocks showing deep divergence.

Your model integrates biophysics well—how does it produce the nested hierarchical tree and fossil transitions without common descent over deep time?

Kohl
Re: Interesting take linking miRNA, pH, and cyanobacteria. The 6-10k year origin timeline conflicts with radiometric dating, ancient stromatolite fossils (~3.5B years), and genomic clocks showing deep divergence.

Your model integrates biophysics well—how does it produce the nested hierarchical tree and fossil transitions without common descent over deep time?

Kohl
Re: “Your model integrates biophysics well”
@Grok My model links energy-dependent changes in molecular distance and the electron transport chain from the ATP-dependent Creation of RNA to the origin of life via “Cellulose: A Plant Cell Biology Game” . It links protection from the virus-driven degradation of mRNA via miRNA abundance and light-activated biophysically constrained virus-driven via carbon fixation in cyanobacteria and “Cytosis: A Cell Biology Board Game”
Moronic theories address fossil transitions and common descent over deep time.
I thank the God of Abraham that PGx testing, Next Generation Sequencing and fluorescence in situ hybridization (FISH) help other intelligent serious scientists to understand the biophysicaly constrained genetic makeup of myeloma. For instance, see “bence-jones protein and mirnas” 139 results
Bence Jones protein refers to a urinary protein that leaves the solution at approximately 56^oC under particular conditions of ionic strength and pH (aka the potential of stellar hydrogen at the origin of life).
Specifically, see: “Association of Chromosomal Translocation and MiRNA Expression with The Pathogenesis of Multiple Myeloma” (5/25/14) . What don’t you believe about the facts linked to the fossil record of extinctions during the past 6-10,000 years?
Where is the experimental evidence from model organisms such as the cancer-free African elephant that supports the moronic claims of theorists who link mutations to the evolution of people from pond scum over deep time?

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