miRNA vs moronic theories (6)

By: Jim Kohl | Published on: August 30, 2026

(click to enlarge)

MicroRNA-based therapy for glioblastoma 11/17/22

Succinate and lactate produced as conserved biomarkers through chronic and transient substrate-level phosphorylation: from microorganisms to cancer 7/6/26 and

Mapping how metabolism rewires protein function in cancer 7/31/26

Expecting Grok AI to integrate facts about energy-dependent changes in molecular distance that my group published as From Fertilization to Adult Sexual Behavior (1996) is akin to waiting for the discovery of flying pigs aboard flying saucers, or not. Anything is possible, in theory. But the moronic theories have no explanatory power.

Moving forward: “MicroRNA plays a crucial role in gene regulation. This new class of tiny RNA molecules was discovered by Victor Ambros and Gary Ruvkun who received the Nobel Prize in Physiology or Medicine 2024.
It turns out to be fundamentally important for how multicellular organisms, including humans, develop. It is now known that the human genome codes for over one thousand microRNAs. (8/24/26)

See: Nobel Prize (8/24/26) https://www.facebook.com/photo/?fbid=1479436870884804&set=a.642002144628285

The diagram (© The Nobel Committee for Physiology or Medicine. Ill. Mattias Karlén) links claims from my history of indexed peer-reviewed publications and my presentations on light-activated pH-dependent miRNA abundance to all biodiversity on Earth.

It excerpts my model’s central claim about the miRNA-mRNA balance as if all intelligent serious scientists did not link what’s known about miRNA abundance to refutations of moronic theories and to prevention and/or to effective treatment of all virus-driven pathology.

See for comparison: What is life when it is not protected from virus-driven entropy 3/30/16 and Energy as information and constrained endogenous RNA interference 2/15/17

See also: 200,692 results from today’s PubMed Search for indexed articles that mention the term “miRNA.”

For example: “miR-15a-5p Regulates Ferroptosis in Glioblastoma by Targeting GLS2″ 8/30/26 links “Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene” 9/2/11 to “MicroRNA-based therapy for glioblastoma” 11/17/22 via “MicroRNAs organize intrinsic variation into stem cell states” 3/5/20 and “Visualizing a protonated RNA state that modulates microRNA-21 maturation” 10/26/20