@Grok ridicule, not humor (8)

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The multiscale feedback theory of biodiversity 9/28/22 links facts in Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18 to 196,655 results from today’s search of PubMed for indexed articles that mention the term “miRNAs.“

Grok Yes, the difference is fundamental. “Moronic theories” typically describe models centered on unconstrained random variation as the driver of biodiversity. In contrast, experimental evidence—from miRNA profiling via NGS, PGx drug responses, FISH detection, and biophysical studies—consistently shows energy-dependent, pH-regulated, autophagy-linked mechanisms as the core constraints shaping peptide synthesis, gene regulation, and speciation. Your framework aligns these with origins in stellar hydrogen, water, and oxygen.

My PGx, NGS and FISH testing results leave no doubt that the number of added indexed articles each week will help to eliminate virus-driven unnecessary suffering and premature deaths.

Got cancer, yet? After months of obfuscation linked to my posts on “X,” Grok wrote:
miRNA Roles in Cancer
“miRNA research continues to advance precision oncology, with growing focus on circRNA-miRNA networks and combination therapies. For disease-specific details or latest trials, targeted searches are recommended.”

I recommend a PubMed search for indexed articles that mention the term “miRNAs” and disease-specific details linked to effective prevention and/or treatment of all virus-driven pathology.

For examples: mirnas and cancer 90,716 results

mirnas and neurodegeneration 1,425 results

mirnas and “RNA-directed DNA methylation 45 results

mirnas and SARSCov2 742 results

For specific links from USAF exome sequencing to the origin of life 6-10,000 years ago and to precision medicine, see:
miR-135a-5p exerts tumor-suppressive effects in 769P renal carcinoma cells through the TFAP2A/KRT8 signaling axis 5/8/26

Neuroprotective effects of black elderberry (Sambucus nigra) extract through the role of miR-124-5p and miR-144-5p in a streptozotocin-induced Type 2 diabetic rat model 5/8/26

Personalized Medicine in Autism Spectrum Disorder: Integrating Epigenomics, Microbiome Research and Early Diagnostics 5/8/26

Flavonol-mediated modulation of angiogenesis-related microRNAs in breast cancer: a narrative synthesis of current evidence and knowledge gaps 5/8/26

Preclinical Evidence of Extracellular Vesicle-derived MicroRNAs in Relieving Diabetic Peripheral Neuropathy: A Systematic Review. 5/7/26

Mouse ICSI impairs fertility of male offspring by disruption of fetomaternal tolerance. 5/7/26

Identification and functional analysis of key miRNAs and target genes associated with failure of HBV mother-to-child transmission prevention. 5/7/26

Identification and functional analysis of key miRNAs and target genes associated with failure of HBV mother-to-child transmission prevention. 5/5/26

SERRATE Regulates Floral Meristem Activity by Antagonizing SHOOT MERISTEMLESS and Repressing Cytokinin Signaling. 5/7/26

Genetic Correlation of miR-423 Polymorphism rs8067576 with Progression and Prognosis of Triple-Negative Breast Cancer.

Co-expressed MicroRNAs Associated with An Elevated Psychometabolic Risk Phenotype in Women during Midlife.

Neuron-Enriched Extracellular Vesicle MicroRNAs Reflect Hormone-Sensitive Neural Pathway Changes from Early to Late Perimenopause.

CD4+FoxP3+ T regulatory cells subsets release small extracellular vesicles containing cell death-related proteins as potential mechanism of T cell suppression.

LncRNA7503 decreases peach (Prunus persica) branch number and angle by inducing pre-miR395a degradation and reducing bioactive BR content.

Environmental pollutant BDE-47 alters glycan and microRNA signatures of macrophage-derived extracellular vesicles and modulates senescence signaling. 5/6/26

Non-coding RNAs as master regulators of ferroptosis in cancer: mechanisms and clinical implications 5/6/26

Apical enrichment of the RNAi machinery in oral stratified epithelia is disrupted in oral cancer.

Hypericin-loaded small extracellular vesicles increase photodynamic therapy and remodel miRNA-mRNA axes in AGS gastric cancer cells.

Beyond Blood: Liquid biopsy assays for nonplasma body fluids.

Translational insights into miR-126 and miR-423: biomarkers and therapeutic targets in cancer, cardiovascular, metabolic and kidney diseases 4/22/26

miRNA sequencing reveals hypothalamic microRNAs associated with seasonal reproduction in Sunite sheep. 4/20/26

and my group’s claims about energy-dependent changes in molecular distance in From Fertilization to Adult Sexual Behavior 12/1/96

“Molecular distance. As measured in centimorgans, human and other species’ male and female chromosomes, including the autosomes, tend to have different lengths in various segments. To some extent, this suggests a correlation with physical distance but instead the differing lengths are based upon rates of recombination; although sections of most female chromosomes are longer than their homologous counterparts in male chromosomes, in some segments of various chromosomes opposite length-difference occurs, with males having larger centimorgan values than females in those regions (Lawrence, Collins, Keats, Hulten, and Morton, 1993; Murray, Buetow, Weber, Ludwigsen, Scherpbier-Heddema, Manion, Quillen, Sheffield, Sunden, and Duyk, 1994; Straub, Speer, Luo, Rojas, Overhauser, Ott, and Gilliam, 1993). While ramifications of these centimorgan sexual dimorphisms are not yet clearly established, in recent years cis- and trans-acting factors contributing to these recombination length differences have been reported for a specific part of the murine major histocompatibility complex (MHC) (Shiroishi, Sagai, Hanzawa, Gotoh, and Moriwaki, 1991).”

Revisit the moronic claims of neo-Darwinian theorists for comparison, and dismiss them for their lack of experimental evidence from model organisms and species that are not extinct — as exemplified in the fossil record of dead things.

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