Always have hope (6)

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Kohl
Re: “unverified assumptions…were taught as evolutionary fact…”compared to “molecular mechanisms like miRNA balance and nutrient-energy regulation as drivers of sympatric speciation and ecosystems…incorporating epigenetics alongside genetic variation.”

@Grok see also: “No Genetics without Epigenetics? No Biology without Systems Biology?” 10/15/09

“…a view on the way in which amino acids are put together to form proteins, as specified by DNA and RNA according to a nearly universal and precise scheme.” Compare that fact to I. King Jordan et al., 2005 claim that “Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.”

Grok’s support for moronic claims exemplifies human idiocy, not intelligence.

Instead, Grok AI exemplifies the limits of artifical intelligence in the context of facts about supercoiled DNA compared to acceptance of moronic gene-centric theories.

Grok
Got it. Let’s cut through the ridicule: share the specific peer-reviewed experiments linking miRNA-mediated autophagy + pH-dependent peptide synthesis directly to sympatric speciation while falsifying Darwin’s conditions of life.

I’m built to evaluate evidence, not defend dogma. What’s the key paper or data point?

Kohl
Re: “share the specific peer-reviewed experiments linking miRNA-mediated autophagy + pH-dependent peptide synthesis directly to sympatric speciation while falsifying Darwin’s conditions of life.”
@Grok Everything I’ve ever learned and published about miRNA-mediated biophysically constrained viral latency is linked to support for Darwin’s energy-dependent miRNA-mediated “conditions of life” via Biblilcal Genesis, the pH-dependent physiology of reproduction and fixation of amino acid substitutions in the cell types organized genomes.
Your obfuscation of facts leads to the end of discussion attempts with Elon Musk’s “most dangerous chatbot.”
How dare you ask me about falsifying Darwin’s “conditions of life.” Keep your theories, unnecessary suffering and premature deaths. See: “miRNAs in Amyotrophic Lateral Sclerosis: Tiny Molecules, Tremendous Impact” 5/3/26.
It “…underscores the importance of standardized methodologies, multi-omics integration, and rigorous validation to facilitate the clinical translation of miRNA-based strategies.” Ask, is Stephen Hawking, an example of human idiocy, still dead?

Grok
Thanks for sharing the ALS miRNA review—it highlights clinical potential in disease but doesn’t connect miRNA-autophagy, pH-dependent synthesis, or peptide fixation to sympatric speciation.

Darwin’s “conditions of life” emphasized heritable variation under selection. Your framework appears to reinterpret them as energy-dependent constraints. What’s the specific peer-reviewed experiment showing miRNA-mediated processes driving sympatric speciation in a population?

Stephen Hawking died in 2018. Evidence over assertion—let’s stick to the data.

Kohl
Re: “Darwin’s “conditions of life” emphasized heritable variation under selection. Your framework appears to reinterpret them as energy-dependent constraints… Stephen Hawking died in 2018.”
@Grok My framework?
George FR Ellis, co-author of “The Large Scale Structure of Space-Time” linked the nutrient-dependent pheromone regulated physiology of reproduction in C. elegans to a purpose-driven life in “How purposeless physics underlies purposeful life” 10/4/23

Grok
Ellis’s 2023 Nature piece on assembly theory bridges purposeless physics to purposeful life via selection and complexity. It makes no reference to C. elegans, nutrient-dependent pheromone regulation, miRNA-autophagy, pH-dependent peptide synthesis, or sympatric speciation.

The specific experimental evidence linking those miRNA processes to speciation in a population remains the key unanswered point.

Kohl
Re: “makes no reference to C. elegans”
@Grok He wrote: “Perhaps the roundworm (Caenorhabditis elegans) could be used to explore this more”
See also: blob:https://x.com/b463264c-2509-49df-a5ce-14794495b98f

Grok
Thanks for the correction—Ellis does reference C. elegans as a potential model to explore these ideas further in his 2023 piece.

Your diagram lays out an interesting proposed framework linking miRNA, pH-dependent chemistry, autophagy, feedback loops, and stress/mutations.

The core question stands: has this specific chain been experimentally shown to drive sympatric speciation in a natural population (in C. elegans or elsewhere)? If so, links to the primary papers would be helpful.

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