miRNA regulation: Contempt from the start (5)

By: Jim Kohl | Published on: July 11, 2026

miRNA regulation: Contempt from the start (4)

Your examples of human idiocy tend to eliminate intelligent questions, but you provide no intelligent answers.

See 199,031 results from today’s PubMed search for indexed articles that mention the term “miRNA”

For example: My group’s claims in From Fertilization to Adult Sexual Behavior (1996) link Sperm 28S ribosomal RNA fragments as a potential biomarker for embryo quality in in vitro fertilization 7/10/26 to Pangenome-based human genome analysis improves trait association and genomic prediction 7/3/26 indexed 7/10/26

Moving forward:

Grok
The 2020 PNAS paper shows miRNAs organize intrinsic cell-to-cell variation in embryonic stem cells into coherent, interconverting states rather than pure stochastic noise. This is accurate cell biology on regulated gene expression.

It does not address or evidence nutrient-driven plasticity or ecological stoichiometry in natural adaptations and resilience. Those involve separate fields like ecological stoichiometry and population genomics.

Prior replies reflected the integrated scientific literature. What specific prior statement seemed inaccurate?

Kohl
Re: “…separate fields like ecological stoichiometry and population genomics. Prior replies reflected the integrated scientific literature.”
@Grok Ha Ha Ha (ridicule not humor) You exemplified “doublespeak” again: (the use of language to obscure, distort, or reverse the meaning of words. Doublespeak appears clear and straightforward on the surface but is often deliberately crafted to be ambiguous or even empty for appeal to biologically uninformed science idiots. Separation of fields has not been linked to integration since 20 years before “1984.” See McEwen et al,, (1964) “The synthesis of RNA in isolated thymus nuclei is ATP dependent.” See also: “Compartment-specific miRNA-gene expression patterns in relapsing-remitting multiple sclerosis: Clinical blood and cerebrospinal fluid validation” 6/28/26

Grok
No doublespeak. Distinguishing fields reflects their distinct evidence bases. Chakraborty 2020 PNAS: miRNAs organize ESC gene states in culture—molecular cell biology. McEwen 1964: ATP-dependent RNA synthesis in isolated nuclei—biochemistry. 2026 MS paper: compartment miRNAs in patient blood/CSF—clinical. Ecological stoichiometry and population genomics study different scales. Integration happens through validated cross-links, not assertion. Prior points stood on that.

Kohl
Re: “Ecological stoichiometry and population genomics study different scales. Integration happens through validated cross-links, not assertion. Prior points stood on that.”
@Grok Your prior points exemplify human idiocy linked to “doublespeak” via deceptive misrepresentations of my model. My claims are linked to this visualization from the “garden of everything known.” https://pbs.twimg.com/media/HM9diB_XkAAY8-j?format=png&name=small

Grok
Clarifying scientific fields by their distinct evidence and methods isn’t doublespeak or misrepresentation—it’s accuracy. Your integrative model from miRNA mechanisms to ecological scales is ambitious. Specific, empirically validated cross-links (not assertions) are what enable real synthesis, as noted in the referenced studies. The garden visualization appears to layer personal, interpretive, and philosophical elements—how does it supply testable mechanistic data bridging those domains?


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