miRNA interpretive models (2)

(click to enlarge)

miRNA interpretive models (1)

@Grok My group’s “single synthesis” “From Fertilization to Adult Sexual Behavior” (1996) was validated by all subsequent works published by intelligent serious scientists. For example, see: “The Dynamical Emergence of Biology From Physics: Branching Causation via Biomolecules” 1/24/19

My PGx, NGS, and FISH testing results link the energy-dependent miRNA/mRNA balance to biophysically constrained ecological adaptations via 201,067 results from today’s PubMed search for indexed articles that mention the term “miRNA” and my model blob:https://x.com/9a3e7448-ee95-4fb0-9b4a-9e74d8a5280a:

What makes you think you can continue to exemplify human idiocy. See: “MIT published a brutally honest report on what AI is doing to students.”

Grok

James V. Kohl’s post defends his 1996 paper “From Fertilization to Adult Sexual Behavior” as the foundational synthesis linking nutrient-dependent miRNA/mRNA balance to molecular epigenetics in sexual development and ecological adaptations.
The included diagram models connections from sunlight, quantum physics, and chemistry through molecular epigenetics and miRNA-mediated amino acid substitutions to processes like neurotransmission, reproduction, HPA axis function, and contrasts RNA events with virus-driven mutations and entropy.
Kohl cites his PGx/NGS/FISH testing results and over 201,000 PubMed miRNA papers as validation of energy-dependent, biophysically constrained adaptations via autophagy and pH-dependent peptide synthesis rather than accumulated mutations.

Kohl

Re: “…the foundational synthesis linking nutrient-dependent miRNA/mRNA balance to molecular epigenetics in sexual development and ecological adaptations.”
@Grok USAF training to become a medical laboratory scientist helped Kohl link the energy-dependent “foundational synthesis” from claims in McEwen et al., (1964), Dobzhansky (1964), and glucose testing with glacial acetic acid in the lab to prevention and/or effective treatment of all virus-driven pathology via his 100% VA disability award for chemical exposure linked to broken hydrogen bonds reported in the context of the “Energetic basis of hydrogen bond formation in aqueous solution https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9463299 8/12/22
Intelligent people are not surprised to see theorists continue to fight against the energy-dependent “foundational synthesis” that Merian (1679) linked from the diet of caterpillars to Darwin’s (1859) “conditions of life” sans moronic theories, facts about peptide synthesis and effective treatments of all virus driven mental and physical pathology linked to God’s Creation of the peptide/hormone insulin.

Grok

The 1996 Diamond, Binstock and Kohl paper discusses molecular epigenetics in sexual development beyond the classic gonad-hormones-behavior path. Ellis and Kopel’s 2019 paper on dynamical emergence via biomolecules does not cite it. The ~201000 PubMed miRNA results come from many independent labs worldwide confirming regulatory roles and autophagy links separately from any single model.

Kohl

Re: “The 1996 Diamond, Binstock and Kohl paper discusses molecular epigenetics in sexual development beyond the classic gonad-hormones-behavior path. Ellis and Kopel’s 2019 paper on dynamical emergence via biomolecules does not cite it. The ~201000 PubMed miRNA results come from many independent labs worldwide confirming regulatory roles and autophagy links separately from any single model.”

@Grok Ha Ha Ha (ridicule, not humor)
For obvious reasons, Ellis (1/8/13) did not cite Kohl but validated Kohl’s model “Nutrient-dependent/pheromone-controlled adaptive evolution: a model” 6/14/13 in 2014, after Ellis linked “Affective Neuronal Selection: The Nature of the Primordial Emotion Systems” 1/8/13 to the “Energetic basis of hydrogen bond formation in aqueous solution” 8/12/22

Theorists who refused to follow the extant literature exemplify human idiocy for comparison to more than 60 years of scientific progress.

Grok

The MIT report covers generative AI effects on student learning, mastery, isolation and assessment at MIT. It does not evaluate AI handling of scientific claims. Ellis and Kopel’s 2019 paper on branching causation via biomolecules does not cite the 1996 Diamond, Binstock and Kohl work. PubMed’s roughly 201000 miRNA articles come from independent labs worldwide, separate from any single model.

“Energetic basis of hydrogen bond formation in aqueous solution” 8/12/22 linked the effects of glacial acetic acid on broken hydrogen bonds from my 100% VA disability rating to Molecular mechanisms and translational potential of plant-derived nanovesicles in skin care and regeneration 8/27/26

“This review systematically delineates the biogenesis pathways of PDNVs-including the multivesicular body (MVB) and exocyst-positive organelle (EXPO) routes-and characterizes their complex cargo, which encompasses functional proteins, regulatory microRNAs, and bioactive secondary metabolites.”

For comparison, see the claims of moronic theorists who start with the automagical emergence of energy from the cosmic void and mathemagical evolution of skin cell differentiation to all biodiversity on Earth.

Never forget, many of the first responders to the attack on 9/11/11 had training to handle Hazardous Materials (HazMet training).

“This 40-hour course, based on NFPA® 470: Standard for Hazardous Materials/Weapons of Mass Destruction Emergency Response Personnel Professional Qualifications and NFPA® 470 standard, provides participants with HAZMAT-specific response knowledge and skills, enabling them to respond safely and effectively to a suspected incident at the hazardous materials technician level.”

During my USAF training to become a combat ready medical laboratory scientist in the early 1970’s, no one mentioned that the low water content of glacial acetic acid used to test for glucose linked broken hydrogen bonds to all forms of stress linked virus-driven pathology via reports from 1964 on gene expression in DNA base pairs in solution and fixation of amino acid substitutions in microtubules of cell types via supercoiled DNA.

I sat next to a Broward County, Florida fire-fighter and HazMat trainer during a 9/11/26 Public Memorial Service who reminded me of risks to veterans and first responders linked to facts, which have since been linked to unnecessary suffering, and to my premature death.

But, I would do it all again “For God and County” and to “Honor the Fallen.”

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