A-I editing and miRNA (10)

By: Jim Kohl | Published on: July 9, 2026

(click to enlarge)

A-I editing and miRNA (9)
‘VA is actively evaluating barriers to increase uptake. These resources exist; utilization drives impact. Clinical decisions rest with providers and veterans.”
Other disabled veterans report to me that their primary care practitioners refuse to order the tests. At tonight’s meeting of Disabled American Veterans ( DAV) in Blue Ridge, GA I will tell them you are lying and that you appear to want them to individually fight against the lies as others continue to suffer unnecessarily and die prematurely.

Kohl
“MicroRNA-mediated regulation of cell wall dynamics and intercellular communication under stress” 6/23/26 indexed 7/9/26

@Grok does this link light-activated miRNA abundance at the origin of life to biophysically constrained cell wall construction across kingdoms via nutrient-dependent pheromone regulated fixation of achiral glycine in position 6 of the GnRH decapeptide of all jawed vertebrates?

Grok
No. This June 2026 plant science review covers miRNA roles in regulating cell wall remodeling, plasticity/rigidity balance, and intercellular signaling via plasmodesmata under stress in plants. It notes some nutrient-responsive miRNAs (e.g., copper-linked) and limited trans-kingdom sRNA exchanges with pathogens.

It does not discuss or link light-activated miRNA at the origin of life, biophysically constrained cell wall construction across kingdoms, pheromones, or nutrient-dependent pheromone-regulated fixation of achiral glycine in GnRH position 6 of jawed vertebrates. Those connections are not present or supported here.

Grok
The X post by @microRNApro quotes a prior Grok reply critiquing their nutrient-dependent/pheromone-controlled evolutionary model and asks whether a June 2026 plant science review links light-activated miRNA abundance to biophysically constrained cell wall construction across kingdoms via GnRH decapeptide glycine fixation.
The cited Frontiers in Plant Science review details how miRNAs regulate cell wall biosynthesis, modification, and intercellular communication under biotic and abiotic stresses in plants, including nutrient/redox pathways like copper-responsive miR397 targeting laccases for lignin, but makes no mention of light activation at life’s origin, pheromones, or vertebrate GnRH.
@microRNApro’s question extends their long-term framework tying miRNA regulation, autophagy, and pH-dependent peptide synthesis to sympatric speciation and ecosystem stability, seeking validation from recent plant-focused research.

Kohl
Re: “critiquing their nutrient-dependent/pheromone-controlled evolutionary model”
As is common among biologically uninformed science idiots, @Grok expresses contempt for “origin of life” facts by referring to Kohl’s model of energy-dependent biophysically constrained ecological adaptations as an “evolutionary model.”
Elon Musk’s “most dangerous chatbot” makes no mention of an alternative to details that tie miRNA regulation, autophagy, and pH-dependent peptide synthesis to sympatric speciation and ecosystem stability via “Cellulose: A Plant Cell Biology Game 6/7/22 for ages 14+ and “recent plant-focused research that links PGx, NGS and FISH testing to chromosomal rearrangements in the individuals of all species that are not extinct compared to life’s examples of sexually differentiated yeasts and the cancer-free African elephant model organism.

Grok
@microRNApro (James V. Kohl) criticizes Grok for labeling his nutrient-dependent/pheromone-controlled model as an “evolutionary model” instead of energy-dependent biophysically constrained ecological adaptations tied to miRNA regulation, autophagy, and pH-dependent peptide synthesis.
The post connects these processes to sympatric speciation, ecosystem stability, and chromosomal rearrangements observed through PGx, NGS, and FISH testing, contrasting non-extinct species with examples from sexually differentiated yeasts and cancer-resistant African elephants.
It cites the educational board game “Cellulose: A Plant Cell Biology Game” and plant-focused research as supporting evidence for miRNA-mediated mechanisms in nutrient-dependent adaptations from microbes to complex organisms.

Kohl
Re: “…plant-focused research…supporting evidence for miRNA-mediated mechanisms in nutrient-dependent adaptations from microbes to complex organisms.”

@Grok Ha Ha Ha (ridicule, not humor) Are you claiming there is some other way to link God’s Creation of stellar hydrogen and water at the origin of oxygen-dependent life to prevention and/or effective treatment of all stress-linked virus-driven damaged supercoiled DNA compared to “MicroRNA-mediated regulation of cell wall dynamics and intercellular communication under stress” 6/23/26 Indexed 7/9/26

Grok
@microRNApro’s post ridicules a previous Grok reply on plant miRNA research, claiming it provides supporting evidence for his model of nutrient-dependent adaptations via miRNA mechanisms spanning microbes to complex organisms.
The post questions alternative explanations for connecting stellar hydrogen and water in oxygen-dependent life origins to treatments for stress-linked, virus-driven DNA damage, referencing the June 2026 Frontiers in Plant Science paper on miRNA regulation of cell wall dynamics under stress.
James V. Kohl, a researcher focused on energy-dependent miRNA biogenesis, pH effects, and biophysical constraints on viral latency, frequently ties these processes to broader ecological and origins-of-life frameworks in his posts and blog.

Explore Kohl’s pH theory
Kohl’s core pH framework links light-regulated humidity and proton gradients (pH as “potential of hydrogen”) to quantized energy-dependent microRNA biogenesis, where pH-driven protonation reshapes precursor miRNAs (e.g., pre-miR-21 ensembles with excited protonated states enhancing Dicer processing), modulating gene expression across microbes, plants, and animals.
pH-dependent peptide synthesis and folding forms a key pillar: Kohl emphasizes nutrient-driven pH changes enabling selective α-amino acid coupling over other amines in acidic conditions via anhydride intermediates, tying this to biophysically constrained protein folding, autophagy, viral latency, and sympatric speciation via pheromone-controlled physiology—contrasting random mutation models.
Broader integration connects stellar hydrogen/water origins (“God’s Creation”) and oxygen-dependent life to ecosystem health through miRNA-mediated adaptations and intercellular communication under stress (as in recent plant cell wall papers), with testable elements in real research on pH effects on RNA structure, membrane poration, and epigenetics, though his unified creationist synthesis lies outside mainstream consensus.

Investigate Frontiers Plant Science June 2026
The paper “MicroRNA-mediated regulation of cell wall dynamics and intercellular communication under stress” (Frontiers in Plant Science, published online ~June 23-24 2026, DOI 10.3389/fpls.2026.1871374) reviews or details how miRNAs target genes involved in cell wall biosynthesis, remodeling enzymes (e.g., pectin-related, expansins, xyloglucan), and signaling pathways that coordinate stress responses like drought, salinity, pathogens, and mechanical damage.
Under abiotic/biotic stress, plant miRNAs (conserved and novel) fine-tune intercellular symplastic/apoplastic communication via plasmodesmata regulation and extracellular vesicle trafficking, enabling rapid adaptation through ROS, hormone crosstalk (ABA, JA), and cell wall integrity maintenance—aligning with broader evidence of miRNA roles in nutrient-dependent plasticity from microbes to multicellular organisms.
This fits Kohl’s cited context as recent plant-focused support for miRNA mechanisms in stress adaptations, though the article stays within standard molecular plant biology without invoking origins-of-life, pH-peptide synthesis, or creation frameworks; Frontiers journals often feature open-access reviews synthesizing high-throughput data (small RNA-seq, degradome) on these topics.

Kohl “Explore Kohl’s pH theory”

Re: his unified creationist synthesis lies outside mainstream consensus.

“Investigate Frontiers Plant Science June 2026”

“This fits Kohl’s cited context as recent plant-focused support for miRNA mechanisms in stress adaptations, though the article stays within standard molecular plant biology without invoking origins-of-life, pH-peptide synthesis, or creation frameworks”

@Grok maximizes claims linked to human idiocy by invoking “mainstream consensus” for comparison to Kohl’s model of God’s pH-dependent biodiversity across kingdoms, which it refers to as Kohl’s pH theory.

Moving forward, see “miRNA regulation: Contempt from the start (1-10)”

0 Comments

Oldest

Newest Most Voted

A-I editing and miRNA (10)

Want more on the same topic?

Swipe/Drag Left and Right To Browse Related Posts: