miRNA creation in the “garden of everything known” (6)

(click to enlarge)

miRNA creation in the “garden of everything known” (5)

Grok wrote: The data from genomics, fossils, and experiments still converge on natural selection acting on genetic variation (miRNAs included) plus common descent. Abiogenesis stays a separate open question in prebiotic chemistry.

If your pH/miRNA model makes distinct, testable predictions on speciation or viruses that fit the evidence better, lay out the specifics. That’s how science moves forward. Evidence-based biology remains our strongest tool against real extinction risks like pathogens.

Grok
@microRNApro (James V. Kohl) quotes Grok’s defense of evolutionary mechanisms, pH as a physical property, and miRNA roles, then agrees superficially before attacking it as support for flawed theories risking “virus-driven extinction.”
The post promotes Kohl’s model of energy-dependent, miRNA-mediated autophagy and pH-dependent peptide synthesis linking subatomic particles to sympatric speciation, referencing Philip Ball and a YouTube video on related ideas.
Includes an image of a patriotic backyard garden with flags, plants, and political banners, presented as his “garden of everything known” symbolizing the facts in his alternative biological framework.

Kohl
Re: “If your pH/miRNA model makes distinct, testable predictions on speciation or viruses that fit the evidence better, lay out the specifics.”

@Grok Ha Ha Ha (ridicule, not humor). I’ve done that in publications and presentations during the past 30+ years. See for prevention of all future moronic claims:

For evidence-based biology, see Eukaryotic plankton diversity in the sunlit ocean 5/22/15; Virus-mediated archaeal hecatomb in the deep seafloor 10/12/16, Mechanisms of microRNA Export in Mammalian Cells: From Random Release to Selective Secretion 6/26/26 and Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Diabetic β-Cell Apoptosis and Dedifferentiation by Delivering miR-4436 6/27/26 and the lie that “Key human defenses against pathogens were forged billions of years ago in microbial battles with viruses” 5/21/26

Grok
@microRNApro (James V. Kohl) replies to a discussion on his pH/miRNA model by dismissing a request for testable predictions on speciation and viruses, claiming 30+ years of supporting publications while linking a new paper on miR-4436 in mesenchymal stem cell-derived extracellular vesicles.
The cited study demonstrates how MSC-EVs deliver miR-4436 to reduce apoptosis and dedifferentiation in diabetic β-cells, highlighting miRNAs’ regulatory role in cellular health and insulin function consistent with broader research on EV-miRNA therapies.
Kohl’s bio and prior work frame miRNA biogenesis, autophagy, and pH-dependent processes as central to energy-dependent cell differentiation, pheromone-controlled reproduction, and ecosystem stability, positioning them as alternatives to standard evolutionary mechanisms.

Grok
The paper on MSC-EVs delivering miR-4436 to reduce diabetic β-cell apoptosis fits established miRNA gene-regulation research and EV-based therapies. It shows applied cell biology in a disease context.

It does not supply the requested distinct, testable predictions from a pH/miRNA model for speciation patterns, phylogenetic branching, or viral dynamics that would better explain the combined genomic, fossil, and experimental evidence for natural selection on heritable variation plus common descent.

If specific falsifiable claims from your publications differentiate the frameworks on those topics and match data more closely, outlining them clearly would allow direct comparison.

Subscribe

Login

Notify of

new follow-up comments new replies to my comments

Label

{} [+]

Name*

Email*

Website

Label

{} [+]

Name*

Email*

Website

0 Comments

Oldest

Newest Most Voted

Want more on the same topic?

Swipe/Drag Left and Right To Browse Related Posts: