miRNA related to diseases (1)

By: Jim Kohl | Published on: May 13, 2026

Grok Thanks for sharing the 1996 paper you co-authored with Diamond and Binstock on developmental biology and sexual behavior. miRNA research, including at KAIST on binding site distances and energy effects, is active—but your specific links from that to Trump’s 2020 coronavirus claims via “biophysically constrained biodiversity” represent your individual interpretive synthesis, not mainstream consensus.

Re: Mainstream consensus: See: The Consensus CDS (CCDS) project “[It] … is a collaborative effort to identify a core set of human and mouse protein coding regions that are consistently annotated”

Grok

Thanks for the Williams Textbook excerpt on neural influences converging on GnRH. The 1992 description captures the complex signaling, which later research shows is heavily modulated by miRNA-mediated mechanisms at the post-transcriptional level—energy-dependent via ATP and conserved from yeast pheromone responses to mammalian reproduction, including elephants. Any specific miRNA studies or excerpts linking these you’d like to dive into? I’m here for the evidence.

Re: “specific miRNA studies or excerpts linking these you’d like to dive into? I’m here for the evidence.”

Pattern recognition is required to troubleshoot experimental evidence of biologically based cause and effect in species from microbes to mammals. See: A Practical DNA Molecular Computing Platform for Identifying Expression Patterns of Multiple miRNAs Related to Diseases 5/12/26

It “opens up an avenue for point-of-care clinical diagnosis of early-stage diseases.”

See also:

1) “Mediterranean Diet Can Reduce Fat Accumulation and Obesity Progression Through Action of Plant Bioactive Molecules” 5/5/26,
2) “Atorvastatin Attenuates Human Cardiac Fibroblast Activation, with Associated Changes in GATA4/MEF2C and Selected Fibrosis-Related microRNAs” 5/6/26
and
3) “Age-Associated Impairment of Paneth Cells Driven by microRNA-152 Promotes Intestinal Epithelial Vulnerability to Pathological Stress” 5/13/26

Taken together, they link my claims in “Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems” 4/18/18 to healthy longevity via prevention of virus-driven degradation of mRNA across kingdoms at the origin of life 6-10,000 years ago, the biophysically constrained physiology of reproduction, PGx & NGS testing available to US veterans form Baylor Genetics, which helps to prevent medication errors linked to suicide, to effective treatment of cancers, and to all other virus-driven pathology.
When did Grok start promoting the testing instead of moronic theories that link the automagical emergence of energy from the cosmic void to the mathemagical evolution of people from pond scum and non-human primates across deep time vs the mainstream consensus?

See for comparison: A hidden inheritance could explain disease risks beyond DNA 5/6/26

“…what we’re trying to understand is whether there are cases where an epigenetic change triggered by the environment can bypass the mechanisms that normally erase those marks between generations, because it’s adaptive enough to be worth preserving. In other words, epigentic changes may not just be shaping us as individual people; they may have helped shape us as a species. If true, the implications of that could be transformative.”


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