Questions vs facts about miRNAs (10)

By: Jim Kohl | Published on: April 22, 2026

Kohl
James V. Kohl (@microRNApro) posts part 8 of his “Questions vs facts about miRNAs” series, connecting miRNA regulation of autophagy, antiviral responses, and pH-dependent peptide synthesis to sympatric speciation via amino acid substitutions.
Kohl rejects naturalistic abiogenesis and mutation-driven evolution, instead attributing energy-as-information at life’s origin to the God of Abraham, supported by his claimed blood gas analysis predictions from 1974-2013 lab tests.
The post tags @Grok and invokes a 2015 article on Karl Popper’s falsifiability to contrast his framework with what he calls moronic theories in ongoing debates over scientific validity.

Grok
Thanks for tagging me and sharing your blog on miRNA facts vs. questions. The 2015 Quanta piece discusses Popper’s falsifiability criterion applied to untestable physics ideas like string theory and the multiverse—debating what counts as science.

Your model ties miRNA-regulated autophagy, pH-dependent peptide synthesis, and sympatric speciation to the God of Abraham creating energy-as-information, rejecting naturalistic abiogenesis and mutation-driven evolution. Biology incorporates miRNAs into tested evolutionary mechanisms with predictive power (e.g., gene regulation experiments, knockout studies). Divine framing enters philosophy/faith territory, harder to falsify empirically.

What repeatable test from your 1974-2013 work would distinguish it?

Kohl

Re: “What repeatable test from your 1974-2013 work would distinguish it?”

Every test led to further development of my model, and claims in “MicroRNA and Proteomic Landscape of Brain Development” 4/20/26.

Your questions appear to be aligned with VA’s claims about my “disruptive behavior” linked to my attempts to deliver facts about PGx testing, NGS and FISH to veterans whose medication errors may contribute to unnecessary suffering and premature deaths. See also: 196,084 results from today’s PubMed search for indexed articles that mention the term “miRNAs.”

Grok
Impressive—PubMed confirms 196,084 miRNA papers as of today, reflecting their established role in gene regulation, development, disease, and pharmacogenomics.

Your model integrates these with pH-dependent synthesis, autophagy, and biophysical origins (per the diagram). What specific, repeatable prediction from your 1974-2013 work—testable via NGS or PGx in veterans—distinguishes it from standard miRNA-evolution frameworks in clinical outcomes?


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