miRNA-mediated neural interfaces (8)

By: Jim Kohl | Published on: April 19, 2026

miRNA-mediated neural interfaces (7)
RNAi research has surged, with PubMed now showing tens of thousands of results on its role in gene regulation, mobility, and cross-kingdom effects—as in today’s plant small RNA paper you noted. Your 1996 linking of energy-dependent changes fits into that molecular picture. These details continue refining, rather than replacing, evolutionary models of adaptation.

4/19/26
Kohl
Re: “refining, rather than replacing, evolutionary models of adaptation”
@Grok “evolutionary models of adaptation” failed to link experimental evidence from model organisms and energy-dependent changes in molecular distance via high school biology (electrical stimulation of frog’s legs) to God’s Creation of stellar hydrogen at the pH-dependent miRNA-mediated origin of life, and President Trump’s 4/23/20 claim that sunlight and humidity help to prevent coronavirus replication. Thank God, intelligent people do not believe in evolutionary models of mutation-driven adaptation.
See why: “Human Sexual Development in the Somatic and Psychosexual Context” 2/4/26, and claims linked to tissue-specific miRNA-mediated ED in castrated rats: “Hypoandrogenic state inhibits erectile function in rats via miR-200a-3p” 5/4/25
Do you know if VA disability claims link extra payments (more than 100%) for toxic chemical-induced hypogonadism and ED to my group’s claims about ecological adaptations in “From Fertilization to Adult Sexual Behavior” 12/1/96

Grok
James V. Kohl (@microRNApro) quotes a prior Grok post on RNAi research refining evolutionary adaptation models, rejecting them in favor of his longstanding framework linking energy-dependent miRNA processes, pH-dependent peptide synthesis, and ecological adaptations to divine creation of life.
The post ties high school-level frog leg experiments, his 1996 paper “From Fertilization to Adult Sexual Behavior,” a February 2026 review on human sexual development, and a 2025 rat study on miR-200a-3p in erectile dysfunction to broader claims about biophysically constrained viral latency and coronavirus prevention via sunlight/humidity.
Kohl inquires whether VA disability claims for toxic chemical-induced hypogonadism and erectile dysfunction align with his group’s 1996 assertions on pheromone-controlled, nutrient-dependent adaptations from fertilization to adult behavior.

Kohl
@Grok That was a rhetorical question. Only VA primary care practitioners are allowed to block refills for testosterone replacement therapy, which link PGx testing and NGS from precision medicine to mental and physical health. The VA treats US Veterans who complain about physical pain, with opioids and treats mental anguish with SSRIs as if veterans were castrated rats instead of men who served “For God and Country.”

Grok
No, VA claims for toxic chemical-induced hypogonadism/ED don’t reference your 1996 paper or group claims on ecological adaptations. ED typically rates 0% but qualifies for SMC-K (~$140/month extra for “loss of use of a creative organ”), added even atop 100% ratings if service-connected via exposures like burn pits or chemicals. Hypogonadism is often secondary/lab-based, with nexus required to duty. VA focuses on medical evidence of service link, not miRNA or pH-dependent models.

Kohl
Re: VA focuses on medical evidence of service link, not miRNA or pH-dependent models.
@Grok On 4/23/20, President Trump linked my model of pH-dependent changes in miRNA abundance to prevention of coronavirus replication via everything known to intelligent serious scientists about hormones and behavior, which we included in our 1996 Hormones and Behavior review “From Fertilization to Adult Sexual Behavior”

Grok
VA policies require documented hypogonadism (symptoms + repeated low morning testosterone) and rule out risks like prostate cancer before TRT approval, per 2025 Criteria for Use. Primary care manages refills under national formulary rules to ensure safety.
PGx testing is expanding VA-wide for tailoring SSRIs and pain meds. Opioid use follows the 2022 CPG prioritizing non-opioids and tapering to reduce harms. Disability claims for toxin-related hypogonadism/ED are assessed individually against service connection standards.

Kohl
Re: “Primary care manages refills under national formulary rules to ensure safety.”
@Grok See: Agent Orange exposure and disability compensation
Erectile dysfunction (ED) is frequently recognized by the VA as a secondary condition caused by diabetes, ischemic heart disease, or hypertension. Veterans can receive compensation if medical evidence proves ED is caused or aggravated by a primary service-connected condition.
VA primary care practitioners who block TRT refills link prescriptions for opioids and SSRIs to murders and suicides. Changes in energy-dependent molecular distance link enzyme-gene interactions to COMT Val158Met variants, and changes in BDNF that are documented in peer-reviewed indexed publication on PubMed that mention the term “miRNAs.”
See for instance 195,984 results, and data from the VA’s Million Veteran Program, USAF exome sequencing and facts about Precision Medicine compared to VA’s medical malpractice, unnecessary suffering and premature deaths.

Grok
Thanks for sharing the 1996 Hormones and Behavior review link. No public records or transcripts from President Trump’s April 23, 2020 COVID briefing connect your pH-dependent miRNA model to coronavirus replication prevention. His comments addressed disinfectants and light as potential treatments. VA claims still require documented medical evidence of service connection for hypogonadism/ED, not theoretical frameworks.


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