miRNA abundance vs circular arguments (2)

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miRNA abundance vs circular arguments (1)
Grok, a witless bot, can now renew its battle of wits with DeepSeek.com 4/30/25 and Philip Ball “Why the Human Genome’s Tangled Physicality May Confound AI 6/18/26, against claims that:
“Experimental evidence of quantum coherence in biology (e.g., photosynthesis, electron tunneling) across kingdoms, from microbes to humans, suggests that quantum effects could have supported RNA-based regulation, including proto-miRNA systems, in early life. This challenges the idea that miRNA systems evolved much later. Quantum coherence likely facilitated energy-dependent processes (e.g., RNA synthesis, stability) in prebiotic or early cellular systems, potentially enabling miRNA-like regulation at the origin of life. In modern organisms, quantum coherence in reproduction and energy transfer continues to support miRNA function, influencing gene expression and development across kingdoms.”

Grok
The X post links to the author’s blog post arguing quantum coherence in processes like photosynthesis and electron tunneling enabled proto-miRNA systems and RNA regulation at life’s origin, challenging claims of later miRNA evolution while tying it to modern gene expression and viral defense.
It criticizes AI responses, including from Grok, as relying on circular arguments about genome complexity and evolution, directly referencing Philip Ball’s June 18, 2026 Quanta Magazine article on how the human genome’s non-blueprint physicality may limit AI understanding.
Abundant miRNA research (over 27,000 PubMed results) supports roles in gene regulation and pathology prevention across species, though direct experimental links from quantum effects in early life to miRNA-like systems remain an area of active scientific debate rather than settled consensus.

198,168 results from today’s PubMed search for indexed articles that mention the term miRNA, include:

Cross-kingdom noncoding RNA regulation facilitates Nosema bombycis proliferation

“…established a competing endogenous RNA regulatory network involving N. bombycis-derived lncRNAs, parasite-specific milRNAs, and host-derived microRNAs (miRNAs), revealing intricate molecular interactions that may be implicated in pathogenicity.”

Alkaloids mediated regulation of microRNA in cancer: molecular insights and emerging therapeutic strategies

“…alkaloids and their derivatives possess strong anticancer potential and have emerged as promising pharmacological agents. Numerous alkaloids screened from herbal (medicinal) sources have demonstrated significant antiproliferative and anticancer effects against several cancer types.”

If you still believe in mutation-driven evolution, you exemplify human idiocy.

Co-Expressed MicroRNAs Identify Potential Mechanisms Underlying Risk for Multimorbid Depression and Type 2 Diabetes in Midlife Women

“Experimentally validated mRNA targets related biological pathways were identified, providing multisystem insights into potential mechanisms underlying risk for multimorbid depression and T2D in midlife women.”

Salivary microRNA Profiling of Long COVID Subjects Reveals Host-Encoded Regulators of Inflammation and Viral Persistence

“…selected dysregulated miRNAs. Integrative pathway analyses identified these miRNAs as regulators of core inflammatory circuits, including Ras, MAPK, and NFκB signaling, converging on IL-1β- and TNF-centered networks relevant to both PD and COVID-19.”

miR-150-5p at the Interface of Cancer Biology and Immune Regulation: Dual Roles, Mechanisms, and Therapeutic Opportunities

miRNA-mediated cancer protection: “We further explore miR-150-5p’s regulation of key immune cell subsets-such as macrophages, dendritic cells, T cells, and natural killer cells-and its implications for anti-tumor immunity.”

Why weren’t you told about this in public schools?

The dialectics of cancer: A theory of the initiation and development of cancer through errors in RNAi

Got cancer. Yet? “…epigenetic modification of the promoter site of the mutant gene, specifically methylation of cytosines. In some instances, instead of methylation, the homologous DNA is degraded, leading to loss of heterozygosity…”

Epigenetic regulation of lymphoid specific gene sets

“…tissue- and site-specific DNA demethylation and affect, thereby, accessibility to recombination-activating proteins, transcription factors, and enzymes involved in histone modifications. Both DNA methylation and the Polycomb group of proteins (PcG) function as alternative systems of epigenetic memory in lymphoid cells”

GLP-1 Receptor Agonist Therapy in Cystic Fibrosis-Related Diabetes: Insights from a Pilot Implementation Program 6/22/26

“…the CF population experiences increasing rates of overweight and obesity, particularly with widespread cystic fibrosis transmembrane conductance regulator (CFTR) modulator use. This article describes practical insights from implementing a pilot program evaluating injectable semaglutide, a GLP-1 receptor agonist (GLP-1 RA)…”

See also: “hexokinase and chromosomal rearrangements” 5 results
Glucose catabolism in cancer cells: amplification of the gene encoding type II hexokinase 6/1/96
“This is the first report describing the amplification of a hexokinase gene in a tumor cell line expressing the high glycolytic phenotype.”

When you’re ready to link miRNA abundance from glucose metabolism to prevention of all virus-driven diseases, follow that facts on PubMed, not the claims of moronic theorists who know nothing about epigenetic effects on disease prevention and/or effective treatment.

For example, Reprogrammable bacterial nanosyringes to deliver RNA and gene editors 6/22/26 links Harvard’s patent for naturally occurring “RNA-guided genome engineering” from light-activated carbon fixation at the origin of life via its physiology of pH-dependent pheromone regulated reproduction in Biblical Genesis.

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