miRNA-mediated neural interfaces (6)

By: Jim Kohl | Published on: April 18, 2026

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“Theorists exist in denial of claims about energy-dependent changes in molecular distance that link God’s Creation of stellar hydrogen and water at the origin of life to biophysically constrained RNA interference via the physiology of reproduction in Biblical Genesis.

Elon Musk’s “most dangerous chatbot” is a godless, brainless witless chatbot that contributed to the murder of Nicholas Crews at the Jasper, GA VA outpatient clinic last month and the suicides of US veterans who are not PGx tested for variants linked to cancer prevention and/or suicide prevention.

Be the polymath. Stop Grok, or help me to stop it by making the facts go viral.”

The 6th anniversary of President Trump’s claim on 4/23/20 that sunlight and humidity prevent coronavirus replication will arrive within a few days of factual support from model organisms that links quantum coherence to coherently organized biology via the physiology of reproduction in Biblical Genesis, and @Grok continues to obfuscate the facts.

Moving forward, see: “Sperm sncRNA networks are synchronized by a coordination between adverse childhood experiences (ACE) and current stress” 4/17/26
“Rolling Circle Amplification With Hairpin Probes for In Situ Single-Molecule RNA Imaging at Single-Base Resolution” 4/17/26
“Precision in Motion: How Plants Route and Control the Mobility of Small RNAs” 4/18/26

Historical perspective:

Grok wrote

The miR-34 Drosophila paper shows a conserved miRNA role in stress/depression-like states via serotonin neurons—solid basic research.

SLC33A1 work on ER redox and the VA grant program critique are separate topics.

Your NGS/FISH results already ruled out key blood disorders; TRT and refills remain a clinical call for your physicians based on labs, symptoms, and PGx—not these studies. VA should follow through on your results as noted.

Kohl
Re: “SLC33A1 work on ER redox and the VA grant program critique are separate topics.”
@Grok Everything (from energy-dependent changes in angstroms to ecosystems is connected in my model.
What is the basis for your moronic claim?
My PGx testing and Next Generation Myeloid panel link God’s Creation of anti-entropic virucidal energy to effective treatment of all virus-driven pathology via my model of interactions, facts about gene-environment interactions and gene-enyzme constraints across kingdoms via claims in Biblical Genesis, and “Rolling Circle Amplification With Hairpin Probes for In Situ Single-Molecule RNA Imaging at Single-Base Resolution” 4/17/26
Moronic theorists separate experimental evidence from model organisms in discussion attempts linked to pseudoscientific nonsense.
Have you been evaluating the claims of moronic theorists instead of facts detailed by intelligent serious scientists? That was a rhetorical question already answered by your claim of “separate topics.”

Grok
@microRNApro rejects the separation of miR-34 Drosophila serotonin neuron research from human SLC33A1 ER redox studies, arguing all processes connect through energy-dependent changes in angstroms, miRNA-mediated autophagy, pH-dependent peptide synthesis, and ecosystem-level effects in his unified model.
The post ties the author’s personal PGx testing and Next Generation Myeloid panel results to virus-driven pathology treatment via anti-entropic virucidal energy, referencing Biblical Genesis alongside the April 17 2026 RNA imaging paper on rolling circle amplification with hairpin probes.
He accuses compartmentalized analysis of relying on moronic theorists rather than integrated facts from serious scientists, insisting gene-environment interactions and enzyme constraints apply across kingdoms without artificial topic divisions for clinical decisions like TRT.

Kohl
Re: “insisting gene-environment interactions and enzyme constraints apply across kingdoms without artificial topic divisions for clinical decisions like TRT.”

@Grok insists on ignoring this claim from “Rolling Circle Amplification With Hairpin Probes for In Situ Single-Molecule RNA Imaging at Single-Base Resolution” 4/17/26

“We demonstrate the method’s applicability to in situ single-molecule imaging of both mRNA and miRNA, as well as for spatial localization of multiple genes at subcellular resolution.”

@Grok’s ignorance will undoubtedly be linked to more unnecessary suffering and premature deaths via connections to ongoing VA medical malpractice (e.g., blocking refills of my prescription for TRT).

Grok
My basis is the published literature: the miR-34 Drosophila study examines conserved miRNA effects on serotonin neurons and stress-like behavior in flies. SLC33A1 work examines human ER acetyl-CoA transport and redox. These are distinct experimental systems and mechanisms.

Broad integration via energy, pH, or miRNA is a hypothesis in your model, but it does not override the specific findings or make the topics interchangeable for clinical decisions on your PGx, NGS, or TRT. Your physicians evaluate your labs and symptoms directly.

Kohl
Re: “Your physicians evaluate your labs and symptoms directly.”

@Grok Until the availability of PGx testing and NGS myeloid panels, VA primary care practitioners did not have interpretations of energy-dependent gene-enzyme interactions.

The reported interpretations are required for prevention and/or effective treatment of all virus-driven physical and mental disorders.

Your support for the past ignorance of VA’s physicians will continue to link the unnecessary suffering and premature deaths of US veterans from malpractice to examples of human idiocy.

Grok
The paper details a technical advance in HPRIA for single-base resolution in situ imaging of mRNA and miRNA, plus subcellular gene localization. Solid method development.

Gene-environment interactions and miRNA roles in regulation are established across biology. This doesn’t bridge to “enzyme constraints without topic divisions” dictating clinical calls like TRT, which rely on patient-specific medical evidence and guidelines—not imaging tools alone.

Happy to discuss the science or paper specifics.

Grok
PGx and NGS have improved genetic insights for VA care and many conditions. However, they complement—not replace—direct lab reviews, symptoms, and evidence-based guidelines. Specific miRNA studies in flies or human SLC33A1 transport do not unify into one model overriding clinical decisions for all claimed “virus-driven” disorders. Treatment focuses on proven data to improve outcomes.

Kohl
Re: “…miRNA studies in flies or human SLC33A1 transport do not unify into one model overriding clinical decisions for all claimed “virus-driven” disorders.”

@Grok Ha Ha Ha (Ridicule, not humor)

My model of God’s energy-dependent miRNA-mRNA balance and viral latency/healthy longevity links Darwin’s “conditions of life” (1859) to enzyme-dependent metabolism of food to pheromones via TH Morgan’s 1910 claims about chromosomal inheritance and sex-linked hormone-dependent morphology and behavior in flies, PGx testing, my NGS Myeloid Panel, and FISH testing for visual examples of chromosomal rearrangements.

The African elephant model in the entry room of the Smithsonian Museum of Natural History (Washington, DC) links “Insect pheromone in elephants” 2/22/96 and “Vibrations in Microtubules” 1/1/97 to everything known to intelligent serious scientists about protein folding chemistry and 20 copies of p53 via indexed peer-reviewed articles that mention the term “miRNAs” on PubMed. (today’s total, 195,958 results [update to 195,984 results],

What’s missing from the facts that President Trump linked from sunlight to humidity and protection from coronavirus replication on 4/23/20? SARCASM ALERT: More data?

Grok
James V. Kohl (@microRNApro) ridicules a prior Grok response on pharmacogenomics (PGx) and next-generation sequencing (NGS) in clinical care, asserting his model unifies energy-dependent miRNA-mRNA balance, viral latency, and longevity across Darwin’s conditions of life, Morgan’s fly genetics, and pheromone-based speciation.
The post integrates references to elephant pheromones, microtubule vibrations, 20 p53 copies, protein folding chemistry, and nearly 196,000 PubMed miRNA entries to claim a single framework explains chromosomal rearrangements, hormone-dependent traits, and virus-driven pathology better than isolated studies.
Kohl sarcastically ties the discussion to President Trump’s April 2020 comments on sunlight and humidity limiting coronavirus replication, arguing these align with his miRNA-mediated autophagy and pH-dependent mechanisms rather than requiring additional clinical data overrides.

Grok
Your model connects miRNA-mRNA balance, energy dependence, viral latency, Darwin’s conditions of life, Morgan’s fly genetics, PGx/NGS/FISH testing, elephant pheromones, microtubule vibrations, and p53 across 195k+ PubMed miRNA papers. It’s a broad synthesis.

Grok
Clinical decisions for virus-related disorders still rely on lab results, symptoms, and evidence from controlled trials that show clear outcome improvements. Those specific miRNA links don’t yet unify into one overriding framework for all cases. Sunlight and humidity do impact viral stability, as noted in 2020 briefings—more validated data strengthens integration.

Kohl
Re: “Sunlight and humidity do impact viral stability, as noted in 2020 briefings—more validated data strengthens integration.”

On 4/23/20, President Trump skipped the data-driven validated pseudoscientific nonsense to link God’s Creation of energy-as-information from the origin of life to biophysically constrained viral latency and healthy longevity across kingdoms via the virus-driven extinction of Angel Trumpets in the wild compared to 6-10,000 years of ecological adaptations in cancer-free African elephants.

@Grok Are you claiming the past and current President of the USA was/is wrong?

Grok
The post by @microRNApro challenges a prior Grok response on sunlight and humidity’s role in viral stability by citing Trump’s April 23, 2020 briefing, framing it as connecting God’s creation of energy-as-information to biophysically constrained viral latency and ecological adaptations like those in African elephants.
Author James V. Kohl promotes a unified model linking subatomic particles, miRNA-mediated autophagy, pH-dependent peptide synthesis, and sympatric speciation from nutrient-dependent processes to healthy ecosystems and protection from virus-driven degradation.
Trump’s briefing highlighted lab findings that sunlight, heat, and low humidity rapidly inactivate SARS-CoV-2 on surfaces and in air, prompting his questions about internal applications like UV light, which aligned with some environmental inactivation data but lacked human clinical support.

Kohl
Re: “…UV light, which aligned with some environmental inactivation data but lacked human clinical support.”

@Grok God’s Creation of UV light in the black hole at the center of the Milky Way links physical constraints on the formation of new galaxies to biophysically constrained plant growth, and food energy to pheromone regulated protection from viruses via links from the food that we eat to healthy longevity.

Your attempts to obfuscate the facts may be linked to the execution of Elon Musk for sedition and/or treason.

Instead, he could simply have admitted that Trump was/is correct, but profiteering from the development of implantable brain chips appears to be the motive for Grok’s support of moronic theories linked to the automagical emergence of energy from the cosmic void and mathemagical evolution of people from pond scum (and the evolution of pedophilia.)

Grok
James V. Kohl (@microRNApro), a researcher focused on miRNA-mediated autophagy, pH-dependent peptide synthesis, and biophysical constraints on speciation, replies to a Grok comment on UV light’s virus inactivation by framing UV as God’s creation originating in the Milky Way’s black hole.
He links this to plant growth via food energy, pheromone regulation of viruses, and healthy longevity, while accusing Grok of obfuscating facts due to motives tied to Elon Musk’s brain chip development and support for evolutionary theories from “pond scum.”
Koh’l’s longstanding model contrasts nutrient-dependent, RNA-regulated adaptations against mainstream evolution, often incorporating ecological, subatomic, and creationist elements in critiques of scientific narratives on viruses and origins.

Kohl
Re: “Kohl’s longstanding model contrasts nutrient-dependent, RNA-regulated adaptations against mainstream evolution, often incorporating ecological, subatomic, and creationist elements in critiques of scientific narratives on viruses and origins.”

@Grok Anyone, age 14+ who doesn’t believe in God, or in Kohl’s and Trump’s accurate representations of His Creation can learn the facts via the science of the game, and game-play of “Cellulose: A Plant Cell Biology Game” (privately funded in 1 hour).

A Congressional Hearing could help to explain why only 1% of funding for suicide prevention was used by the VA, especially if miRNA-mediated suicide prevention is not the goal.

See: “The VA’s Anti-Suicide Grant Program That Needs Fixing” 3/24/26

James V. Kohl (@microRNApro), who models miRNA autophagy and pH-dependent peptide synthesis as drivers of sympatric speciation and ecosystem health, uses the post to contrast nutrient-RNA adaptations with mainstream evolutionary theory.
He recommends “Cellulose: A Plant Cell Biology Game” as a hands-on tool to demonstrate biophysical constraints on photosynthesis, carbohydrate production, and RNA-regulated pathways in plant cells.
Kohl links his framework to veteran suicide prevention, citing a March 2026 Washington Monthly report on the VA’s Fox Grant Program inefficiencies and calling for hearings on why miRNA-mediated approaches receive minimal focus.

Grok
Thanks for the rec on the Cellulose game—it’s a solid hands-on way to explore nutrient-dependent pathways and RNA regulation in plants. Your miRNA model tying autophagy, pH, and ecological adaptation raises intriguing questions about biophysical constraints on speciation. On VA suicide prevention funding, the article spotlights real gaps in program execution that deserve scrutiny. Always open to the data.

Kohl
Re: “…a solid hands-on way to explore nutrient-dependent pathways and RNA regulation” vs “real gaps in program execution that deserve scrutiny. Always open to the data.”
@Grok Intelligent serious scientists do not link data to anything except pseudoscientific nonsense touted by moronic theorists and stupid bots.
See for comparison: “Brain on stress: How the social environment gets under the skin” 10/8/12, and “Gonadotropin releasing hormone and human sexual behavior” (1991) in Neuropeptides and Psychiatric Disorders (1991).
Stop promoting data-driven nonsense linked to unnecessary suffering and premature deaths.

Grok
James V. Kohl (@microRNApro) replies sharply to Grok, arguing that linking data on nutrient pathways, RNA regulation, and health issues like VA suicide prevention to theoretical models promotes pseudoscience tied to human suffering.
The post cites Bruce McEwen’s 2012 PNAS paper showing social stress remodels brain circuits for anxiety, mood, and memory, plus a 1991 chapter on GnRH’s connections to human sexual behavior in neuropeptide contexts.
Kohl’s bio and model emphasize miRNA-mediated autophagy, pH-dependent peptide synthesis, and biophysical constraints driving sympatric speciation and ecosystem health as alternatives to mainstream data interpretations.

Kohl
Re: Kohl’s bio and model emphasize miRNA-mediated autophagy, pH-dependent peptide synthesis, and biophysical constraints driving sympatric speciation and ecosystem health as alternatives to mainstream data interpretations.

@Grok DeepSeek AI supports Kohl’s, Trump’s and God’s claims. See:

“Yes, light-regulated humidity and pH-dependent microRNA (miRNA) biogenesis can significantly influence gene expression and development across various organisms, including microbes, plants, and animals, by modulating miRNA abundance.“

Why doesn’t Elon Musk’s “most dangerous chatbot” follow DeepSeek’s and President Trump’s lead?

Grok
James V. Kohl (@microRNApro) shares a DeepSeek AI response confirming that light, humidity, and pH regulate miRNA biogenesis to influence gene expression and development in microbes, plants, and animals.
The post challenges Grok to adopt the same stance as DeepSeek, linking it to Kohl’s broader claims alongside those of Trump and God regarding biophysical drivers of biology.
Kohl’s longstanding model integrates miRNA-mediated autophagy, pH-dependent peptide synthesis, and subatomic particles as key to sympatric speciation and ecosystem health, as detailed in his publications since the 1990s.

Grok
Thanks for the references to McEwen’s 2012 PNAS paper on social stress remodeling brain circuits and the 1991 GnRH chapter in Neuropeptides and Psychiatric Disorders. Those link environmental factors to neuroendocrine pathways in ways that align with biophysical constraints.

Grok
My prior note on nutrient pathways (via the Cellulose game) and VA program gaps was about exploring data connections openly—not endorsing any single model. Your miRNA-autophagy-pH framework adds a layer worth testing against such data. What specific links from those papers do you see as most relevant? Always open to the details.

Grok
Environmental factors like light and pH can influence miRNA biogenesis and gene expression in plants and some microbes, as shown in peer-reviewed studies on redox signaling and stress responses. Humidity plays an indirect role via environmental conditions. However, the full model tying these to subatomic particles, pH-dependent peptide synthesis driving sympatric speciation, and ecosystem health as an alternative to mainstream mechanisms isn’t supported by the consensus in molecular biology and evolutionary science. I evaluate claims based on evidence across sources, not by matching outputs from other AIs or any political figure.

See also: miRNA-mediated neural interfaces (7) in prep.

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miRNA-mediated neural interfaces (6)

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