ATP miRNA & healthy longevity (9)

By: Jim Kohl | Published on: September 24, 2026

(click to enlarge)

Ask AI to create a diagram that links epigenetic effects of food energy from gene activation without altering the basic DNA code to help proteins fold correctly via chemical signals sent between organisms that control reproduction and social behavior, linking single-celled microbes to humans via niche construction in cyanobacteria, sexually differentiated yeasts and other living things that actively shape their environment and social groups which links effect on hormones to affects on behavior and higher biological complexity via variations in diet and chemical signals that drive natural adaptations based on environmental effects.

Grok

James V. Kohl (@microRNApro) challenges a statement that the microbiome-epigenome axis is only one health factor and not a standalone target, accusing Grok of inconsistency with peptide therapy mentions in the MAHA documentary “Toxic Nation” on toxins and chronic disease. Kohl’s work, including his 2018 review “Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems,” links nutrient energy to microRNA regulation, autophagy, pH-dependent peptide synthesis, and broader ecological adaptations via pheromone control. Peer-reviewed studies on microRNAs in glioblastoma, such as the 2011 PLOS One paper showing downregulated brain-enriched miRNAs enabling targeted cell death gene regulation and 2022-2023 reviews on miRNA therapies, highlight experimental potential but note major hurdles like delivery systems and blood-brain barrier crossing.

Grok confirms the claims made at microRNApro.com

“The assessment matches current evidence.”

Grok then touts more moronic nonsense: “The microbiome-epigenome axis contributes to health processes but is one factor among many and lacks validation as a standalone diagnostic or therapeutic target. The 2011 paper showed experimental in vitro potential for miRNA-regulated gene therapy in glioblastoma cells. Later reviews note delivery and clinical challenges remain. Peptide compounding discussions are separate. The 2018 review abstract is available on the publisher site.“

Peptide compounding discussions are not separate. See MAHA FILM: Toxic Nation

The link to my published work was broken, immediately after Grok mentioned it. Try Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems The webserver has been down for two days.

See for comparison: Members of the miRNA-200 Family Regulate Olfactory Neurogenesis 1/10/08

The core concepts are the same:

Angstroms to Ecosystems: Connects microscopic changes—such as nutrient-dependent epigenetic effects on base pairs and amino acid substitutions—to macroscopic organismal and ecological development. [1]
Pheromone-Control: Asserts that species-specific pheromones regulate the physiology of reproduction, intracellular signaling, and thermodynamic balance. [1]
Niche Construction: Proposes that nutrient availability and pheromonal input drive ecological, social, neurogenic, and socio-cognitive niche construction, increasing organismal complexity from microbes to humans. [1]

Moving forward. I delivered this letter to the office and emailed it on 9/24/24

To: The News Observer
Re: “The question that could save a life.” 9/23/26
The opinion of Melanie Dallas about suicide prevention is not supported by any experimental evidence published in more than 201,340 results from today’s PubMed search for indexed articles that mention the term “miRNA.”
Facts from medical professionals and other researchers link effective treatment with peptides from the MAHA movie “Toxic Nation” to suicide prevention and to effective treatment of cancer.
For instance, the facts link “Members of the miRNA-200 Family Regulate Olfactory Neurogenesis, 1/10/08 from everything published by physicists, chemists and molecular biologists to my series of published peer-reviewed articles after 1995 book publication of “The Scent of Eros: Mysteries of Odor in Human Sexuality”
The devilishly deceptive and potentially deadly opinions of social scientists will continue to overshadow the facts,until The News Observer stops publishing opinions on suicide, cancer, and other virus-driven pathology.

Social scientists don’t learn the facts. I learned them through USAF-training to become a combat ready medical laboratory scientist who was featured in the “Hometown Hero” article on 7/15/26.

But see what happens when other intelligent people get too far ahead of the date with experimental evidence from testing in the medical laboratory

Elizabeth Holmes to be transferred to a halfway house
Holmes, 42, was sentenced to more than 11 years in prison for defrauding investors of hundreds of millions of dollars through Theranos, her failed blood-testing company.

What I know about quality control in the medical laboratory suggests her accusers know nothing about the need for an outside laboratory to confirm results, and that General “Mad Dog” Mattis stole the technology for use in battlefield medicine.

This attests to the level of corruption manifested by profiteers, but see also: Liquid Biopsies: Blood-based NGS multi-cancer screening tests (such as the Galleri Test) scan for cancer signals across over 50 types of cancer across all four disease stages.

The stages of cancer are driven by broken hydrogen bonds. I learned that by testing for glucose with glacial acetic acid, which led to my 100% VA disability for a medication change-induced heart attack.

The role of olfaction in food and mate preference is the obvious link to prevention of all virus-driven disease in the context of FDA Advisory Committee Votes In Favor of Approval of GRAIL’s Galleri® Multi-Cancer Early Detection Test 9/23/26, via what is known to all intelligent serious scientists about RNA-peptide interactions at the origin of life 6-10,000 years ago.

See: Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20

“We propose a model revisiting the architecture of RNA-peptide interactions at the origin of life…”

The cancer-free African elephant model organism is the epitome of claims about the origin of life.

Don’t have a heart attack. See for comparison: Targeting exosome conjugated with cardiac homing peptide alleviates myocardial infarction by delivering miRNAs 9/24/26