miRNA & common ancestry (8)

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miRNA & common ancestry (7)

I reiterate:

Integrated analysis of enzymes, mRNAs, and miRNAs provides insight into the regulatory potential of extracellular vesicles in recipient cell glucose metabolism. 8/6/26

See also:
Extracellular vesicles and their translational therapeutic potential 7/26/26

Moving forward:

Every aspect of energy-dependent biophysically constrained cosmological constants links miRNA-mediated fine-tuning of chromosomal rearrangements to peptide synthesis and healthy longevity via the MAHA movie “Toxic Nation.“

Kohl
Start with God’s Creation of stellar hydrogen in black hole stars and link it to pH-dependent life via miRNA-mediated biophysically constrained cosmological constants and the physiology of reproduction. Be the Bible-based polymath, not the stupid chatbot.

Grok These four papers cover pH-sensitive peptide liposomes for drug delivery, NMR visualization of RNA helix dynamics, miRNA roles in stem-cell gene-expression states, and a pH-dependent protonated conformation in pre-miR-21 that alters Dicer processing. None cite or connect those mechanisms to black-hole emissions, cyanobacterial pheromones, elephants, the claimed protein-folding links, or Genesis. No peer-reviewed evidence supports such connections.

Kohl
Re: “No peer-reviewed evidence supports such connections.”
@Grok Stop lying. Others can see: “Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems” (4/18/18) and/or “The Dynamical Emergence of Biology From Physics: Branching Causation via Biomolecules” 1/25/19
See also, 200,412 results from today’s PubMed search for indexed articles that mention the term “miRNA”

Grok

The Kohl paper presents an author model linking nutrients, pheromones, miRNA/mRNA balance and protein folding to adaptations from microbes to humans. It does not mention black-hole emissions, cyanobacteria, elephants or Genesis. The Ellis paper addresses biomolecular branching from physics to biology via ion channels and similarly lacks those connections. miRNA paper volume does not substantiate the specific claimed links. Independent peer-reviewed evidence for them is absent.

Kohl
Re: “miRNA paper volume does not substantiate the specific claimed links.”
@Grok Ha Ha Ha (ridicule, not humor) If it did not, you could supply links to papers on the automagical emergence of energy from the cosmic void and link them to the mathemagical evolution of people from pond scum for comparison.
Instead, you exist to deny everything known to intelligent serious scientists since McEwen et al., (1964) published Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” with the claim that “The synthesis of RNA in isolated thymus nuclei is ATP dependent.”

Grok

McEwen et al. 1964 established that RNA synthesis in isolated thymus nuclei is ATP-dependent via glycolysis and nuclear processes. That is standard biochemistry.

It supplies no evidence linking black-hole emissions, cyanobacteria, elephants or Genesis to the nutrient-pheromone-miRNA model. The extensive miRNA literature documents many regulatory functions yet contains no independent peer-reviewed support for those specific claimed connections.

Kohl
McEwen et al. 1964 established facts about energy-dependent RNA interference that all intelligent serious scientists continue to link to standard biochemistry.
What claims made by biologically uninformed theorists compare to his group’s claims?
@Grok Ha Ha Ha (ridicule, not humor) That was a rhetorical question.

Grok

McEwen et al. 1964 showed ATP dependence of RNA synthesis in isolated thymus nuclei via glycolysis and nuclear processes. That is standard biochemistry of transcription, not RNA interference (a distinct mechanism identified in the 1990s). The paper supplies no evidence for links to black-hole emissions, cyanobacteria, elephants or Genesis. Independent peer-reviewed work still lacks support for those specific extensions.

Kohl
Re: “standard biochemistry of transcription, not RNA interference (a distinct mechanism identified in the 1990s).”
@Grok Bruce S. MeEwen and Robert L. Moss reviewed the model I first presented in 1992 and told me to avoid gene-centric theories.
That led to the claims in anything I published or presented since then.
What evidence supports moronic gene-centric theories for comparison?

See also: “The glucose ketone index: a compelling mechanistic hypothesis on the path to clinical validation” 8/20/26 @Grok will probably claim this is linked to my personal interpretation of how food energy-dependent pheromone regulated glucose metabolism links achiral glycine in position 6 of the jawed vertebrate decapeptide, gonadotropin releasing hormone (GnRH), and President Trump’s claim that sunlight and humidity protect us from coronavirus replication to claims about peptide therapy in the MAHA movie “Toxic Nation.”

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