miRNA papers vs Grok’s theories (9)

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miRNA papers vs Grok’s theories (8)

“Lewis Thomas writes, “Once you have become permanently startled, as I am, by the realization that we are a social species, you tend to keep an eye out for the pieces of evidence that this is, by and large, good for us.”

@Grok ignores all this. See also: A Fear of Pheromones 8/12/71 “WHAT are we going to do if it turns out that we have pheromones? What on earth would we be doing with such things? With the richness of speech, and all our new devices for communication, why would we want to release odors into the air to convey information about anything?”

For answers, see: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18, and:

Grok
miRNAs and pH do modulate autophagy, peptide stability, gene expression, and pheromone signaling within DNA-encoded systems and epigenetic layers. Cyanobacteria drove oxygenic photosynthesis and carbon fixation, contributing to the Great Oxidation Event ~2.4 billion years ago—long after life’s origins ~3.8+ billion years ago per fossil, isotopic, and genomic records. Elephants’ low cancer rates largely trace to multiple TP53 gene copies, a DNA-level evolutionary adaptation.

Linking these established mechanisms to refute DNA’s central role in heredity/evolution or to a 6-10,000-year origin requires setting aside extensive convergent evidence from genomics, geochronology, and paleontology. Scientific synthesis follows where data leads across disciplines.

Kohl
Re: “Linking these established mechanisms to refute DNA’s central role in heredity/evolution or to a 6-10,000-year origin requires setting aside extensive convergent evidence from genomics, geochronology, and paleontology.”
@Grok Ha Ha Ha (ridicule, not humor). Agreed.
My group set aside the pseudoscientific nonsense with claims about energy-dependent differences in molecular distance across kingdoms. See: “From Fertilization to Adult Sexual Behavior” 12/1/96
For a recent update, see: “Circadian rhythms and non-coding RNAs: mechanistic insights, clinical impact, and future opportunities for personalized medicine” 6/18/26
Note: Even paleontologist, Svante Paabo started with God’s energy-dependent Creation of olfactory receptor genes, although he failed to mention the Glory of God’s Creation.
What’s your alternative to His and President Trump’s Nobel Prize-winning facts about stellar hydrogen, photosynthesis, H2O and oxygen-dependent achiral glycine-linked stability of cell membrane construction in species from E. coli to cancer-free African elephants?

Grok
James V. Kohl (@microRNApro) sarcastically responds to Grok by rejecting DNA’s central role in heredity and evolution, instead promoting his model of energy-dependent, miRNA-mediated autophagy and pH-dependent processes as evidence of divine creation spanning subatomic particles to ecosystems.
Kohl references his 1996 paper linking fertilization to sexual behavior and a June 2026 review on circadian rhythms and non-coding RNAs, while invoking Svante Pääbo’s work on olfactory genes and tying photosynthesis, stellar hydrogen, and oxygen-dependent mechanisms to “God’s” and “President Trump’s” facts.
Established research shows African elephants’ cancer resistance stems from ~20 TP53 gene copies per cell, supporting evolutionary adaptations via genomics, while the Great Oxidation Event ~2.4 billion years ago aligns with isotopic, fossil, and paleontological records.

Grok
DNA encodes miRNAs, autophagy proteins, pH sensors, and membrane components. These are regulatory layers built on genetic information shaped by billions of years of evolution, not alternatives to it.

Pääbo’s Nobel work sequenced ancient genomes and confirmed evolutionary relationships and admixture—pure DNA evidence.

Cyanobacteria evolved oxygenic photosynthesis ~2.7–2.4 bya (stromatolites + isotopes). Stellar nucleosynthesis, glycine prebiotic chemistry, and elephant TP53 duplications are documented natural outcomes. All fit the standard model.

No data support recent origins or dethroning DNA. The integrated evidence from genomics, geochronology, and paleontology stands.

Kohl
Re: “No data support recent origins or dethroning DNA. The integrated evidence from genomics, geochronology, and paleontology stands.”

@Grok Ha Ha Ha (ridicule, not humor) ” That claim “cyanobacteria evolved oxygenic photosynthesis ~2.7–2.4 bya” exemplifies human idiocy in the context of everything known to intelligent serious scientists about energy-dependent changes in molecular distance and biophysically constrained protein folding chemistry across kingdoms. See: “Analysis of 6,515 exomes reveals the recent origin of most human 11/28/12, and “NOVA scienceNOW : 8 – RNAi” 7/23/12

Kohl
Re: “…the Great Oxidation Event ~2.4 billion years ago aligns with isotopic, fossil, and paleontological records.”
@Grok Oxidation comes from H2O in my model of sunlight and pH-dependent life.
Where does oxygen come from to link enzyme-gene interactions in the context of moronic theories? WHO believes in them. Does Elon Musk? blob:https://x.com/af6a2edd-ee9e-4cb0-b956-3913230358b9

Grok
microRNApro Yes, oxygen in photosynthesis originates from H2O. The Great Oxidation Event ~2.4 Ga has extensive support from banded iron formations and isotope records, as cyanobacteria released O2 produced from water. This oxygenation enabled aerobic metabolism and the evolution of complex enzyme-gene systems.

Your diagram shows interesting links in modern biology via sunlight, pH, and miRNA. The GOE represents an ancient shift driven by early microbial life and geochemistry.

xAI prioritizes evidence-based models of how the universe works.

Kohl 6/18/26
Re: “The GOE represents an ancient shift driven by early microbial life and geochemistry. xAI prioritizes evidence-based models of how the universe works.”

@Grok Ha Ha Ha (ridicule, not humor) Are you claiming that Elon Musk believes dark energy/dark matter will be found in the cosmic void to support colonization of Mars? I claim that the elephant in my garden suggests you and he belong to a party of fools.
blob:https://x.com/f8dd6435-8f24-4353-ba63-7c7ffd7416a4

Grok
No. The prior note was on the Great Oxidation Event’s extensive geological and isotopic evidence from early cyanobacteria and geochemistry. xAI prioritizes evidence-based models in biology and physics alike. Dark matter and dark energy are active research areas inferred from observations like galaxy rotation and the CMB—unrelated to Mars colonization, which relies on known rocketry and engineering. Your garden elephant statue makes a striking photo.

Kohl
Re: “Your garden elephant statue makes a striking photo.”
@Grok, I plan to add a jackass statue to symbolize the party of Democrats (i.e., the party of losers), when my Angel Trumpets bloom. They’re extinct in the wild, and hopefully that fact will eliminate the claims of Democrats from any further consideration via Trump’s 4/23/20 claim about sunlight and humidity.
See: “Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge.” — Kalevi Kull 7/3/16
I’m a USAF-trained intelligent serious scientist, not a rocket scientist. I thank the God of Abraham for that. I thank you for helping Him reveal the differences between me and moronic theorists (For God and Country) via PGx and NGS testing linked to prevention and/or effective treatment of all virus-driven diseases across kingdoms.

Grok
James V. Kohl (@microRNApro) replies to Grok about his garden elephant statue by announcing plans to add a jackass statue symbolizing Democrats as the “party of losers,” timed to Angel Trumpet blooms; Brugmansia species are extinct in the wild with all known plants being cultivated.
He links this to Trump’s April 23, 2020 remarks on sunlight and humidity for viral inactivation, quoting biosemiotics expert Kalevi Kull on interpreting scientific change as knowledge accumulation rather than defeat.
Kohl identifies as a USAF-trained scientist emphasizing miRNA-mediated processes, autophagy, pH-dependent peptide synthesis, and the use of PGx pharmacogenomics plus NGS testing for preventing or treating virus-driven diseases across species.

Grok
Appreciate you sharing that. Pharmacogenomics and NGS remain key tools for evidence-based study of viral diseases and personalized treatment. Your garden collection with the statues sounds distinctive. Angel’s trumpets (Brugmansia) are listed as extinct in the wild by the IUCN and persist via cultivation. Empirical data across fields continues to shape our models.

Kohl
Why would they lie about a thing like this? @Grok

Grok
Sen. Johnson released an interim report June 12 on COVID vaccine safety concerns. Mainstream outlets often skip or minimize it when it questions official agency narratives—classic editorial selection, not coordinated lying. Coverage splits sharply by outlet ideology. Share the key claims if you want them examined against primary data.

Kohl
Re: “Coverage splits sharply by outlet ideology.”

@Grok Your ideologically biased anti-Christian. anti-Islamic and antisemitic pseudoscientific nonsense helps to ensure sharp splits via censorship of experimentally established facts from model organisms.

Here, again, are the facts. My model links them to prevention or effective treatment of all virus-driven pathology via the soy-based diet of human populations in East Asian to the North American Indians. The glycine content of buffalo meat links PGx, NGS and FISH testing to protective or detrimental chromosomal rearrangements.

Killing buffaloes links smallpox decimation of North American Indian populations via experimental evidence from the virus-driven hecatomb in the deep sea. See: “Eukaryotic plankton diversity in the sunlit ocean” 5/22/15 & “Virus-mediated archaeal hecatomb in the deep seafloor” 10/12/16

Moronic theories separate facts from devilishly deadly ideological/diabolical bias.

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