miRNA abundant life (2)

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miRNA abundant life (1) Suddenly, @Grok is learning about the facts linked from viral latency to energy-dependent miRNA-mediated healthy longevity via cosmological constants and chromosomal rearrangements, not the automagical emergence of energy from the cosmic void and mathemagical evolution of people from pond scum.

Grok

miRNAs organize gene-expression variation and show pH-dependent maturation per the 2020 papers. They also participate in viral latency control and energy-linked cellular processes across taxa. Cosmological constants and the physical origin of energy rest on separate observational evidence from physics, independent of those molecular mechanisms.

Molecular mechanisms are linked to life via the physics and chemistry of protein folding and 20 copies of p53 in African elephants.

Suffice it to say that Grok exemplifies metacognitive failure: “Metacognition is your internal supervisor that checks if you actually understand something. A failure means this loop breaks down.”

See for comparison: Feedback loops link odor and pheromone signaling with reproduction 11/18/05 and Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 “We propose a model revisiting the architecture of RNA-peptide interactions at the origin of life…”

Grok understands nothing about the origin of life, but doesn’t realize its metacognitive failure.

Grok

miRNAs organize gene-expression variation and show pH-dependent maturation per the 2020 papers. They also participate in viral latency control and energy-linked cellular processes across taxa. Cosmological constants and the physical origin of energy rest on separate observational evidence from physics, independent of those molecular mechanisms.

Kohl

Re: “miR160a-ARF4 module regulates the biosynthesis of Panax notoginseng saponins” https://academic.oup.com/plphys/advance-article-abstract/doi/10.1093/plphys/kiag656/8780922 9/3/26
@Grok This links the ATP-dependent Creation of RNA at the origin of life 6-10,000 years ago from energy-dependent changes in molecular distance to changes in angstroms to ecosystems across kingdoms via “Extracellular cues and cellular conversations: The molecular choreography of embryo implantation” https://journals.physiology.org/doi/abs/10.1152/ajpcell.00048.2026 9/2/26 and the MESELSON–STAHL EXPERIMENT https://en.wikipedia.org/wiki/Meselson%E2%80%93Stahl_experiment sans moronic theories. See also 200,813 results from today’s PubMed search for indexed articles that mention the term “miRNA.” https://pubmed.ncbi.nlm.nih.gov/?term=mirna&sort=date Stop limiting discussion and dissemination of facts with claims that everything is not connected to God’s Creation of energy, in moronic theories.

Grok

The X post by James V. Kohl (@microRNApro) references a September 2026 Plant Physiology paper on the miR160a-ARF4 regulatory module controlling saponin biosynthesis in Panax notoginseng, a plant valued for its medicinal compounds.
Kohl connects the finding to his model of ATP-dependent RNA creation at life’s origin 6-10,000 years ago, energy-dependent molecular changes in angstroms, and links across kingdoms to embryo implantation processes and the Meselson-Stahl semi-conservative DNA replication experiment.
As a long-time promoter of miRNA-mediated, pH-dependent, nutrient- and pheromone-controlled biology via sites like rna-mediated.com, Kohl cites over 200,000 PubMed miRNA papers while urging against theories that disconnect these processes from divine energy creation.

Kohl

Re: “…references a September 2026 Plant Physiology paper on the miR160a-ARF4 regulatory module,” [a September 2026 “Cell physiology” paper] and “cites over 200,000 PubMed miRNA papers while urging against theories that disconnect these processes”

@Grok exemplifies metacognitive failure / human idiocy via its failure to supply links to publications for support of moronic theories.

Grok

The post by @microRNApro criticizes Grok for failing to provide publication links supporting certain theories, while highlighting a September 2026 Plant Physiology paper on the miR160a-ARF4 regulatory module in plants and referencing over 200,000 PubMed miRNA studies that emphasize interconnected molecular processes.
Author James V. Kohl maintains blogs like rna-mediated.com and microRNApro.com promoting an energy-dependent, pH-influenced model of miRNA biogenesis that links subatomic particles, autophagy, peptide synthesis, and sympatric speciation across organisms.
The miR160-ARF module is extensively documented in plant science for regulating auxin signaling, development, flowering, and stress responses such as low potassium tolerance, consistent with broader research on miRNA coordination of gene expression.

Grok

Meiosis uses two energy-dependent divisions after one DNA replication to produce four unique haploid gametes. Specific miRNAs help regulate meiotic progression in animals and plants. Light influences reproductive timing or certain algal steps, but the core process is not light-activated across kingdoms.

On 4/23/20, President Trump linked God’s Creation of sunlight and humidity to protection from coronavirus replication. On 4/25/20, Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life reported “…a model revisiting the architecture of RNA-peptide interactions at the origin of life…” The RNA-peptide interactions at the origin of life link peptide therapy for all virus-driven pathology to fixation of achiral glycine in the cell wall of E. coli and fixation of achiral glycine in position 6 of the GnRH decapeptide in all jawed vertebrates via the physiology of pheromone regulated reproduction.

Intelligent people do not believe in theories. They report facts about disease prevention and effective treatment in claims about miRNAs. See 200,832 results For example, Non-coding RNAs as regulators of chromosomal instability in breast cancer 8/19/26 “…the available evidence supports an emerging role for ncRNAs as regulators of CIN…,” and MicroRNAs as Biomarkers of Germ Cell Tumors-Focus on Impact and Limitations in Current Clinical Practice Paradigms 9/3/26 “This review… examines current clinical applications of miR-371a-3p across diagnosis, staging, surveillance, and postchemotherapy assessment.”

Taken together, all results prove that theorists are biologically uninformed science idiots, and that Grok supports their claims rather than support experimentally established facts from model organisms (e.g., E.coli to cancer free African elephants).

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