miRNA, oxygen, enzymes & life (7)

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miRNA, oxygen, enzymes & life (6) “Grok’s epic failure to link God’s ATP-dependent Creation of RNA from RNA-directed DNA methylation (aka RNA interference) at the origin of life is linked to ineffective prevention and/or ineffective treatments of all virus-driven pathology via the claims of intelligent serious scientists who start with accurate representations of RNAi, light-activated carbon fixation in cyanobacteria and the pheromone regulated physiology of reproduction.

Moving forward:

Kohl
Re: “…rapid adaptations (6-10,000 years) across species, integrating tools like exome sequencing, PGx, NGS, and FISH.”

@Grok’s role as an ideologically biased anti-Christian, anti-Islamic, antisemitic data-driven apathy accelerator can be viewed in the context of its claims about “Kohl’s theory.”

No aspect of energy-dependent biophysically constrained RNA-directed DNA methylation (aka RNA interference/RNAi) and viral latency across kingdoms is based on moronic theories.

See: “An extensive overview on MicroRNAs and pandemic-prone viral diseases: The next frontier in predicting and mitigating pandemics” 5/22/26

“…the next decade is likely to see significant progress in the integration of miRNA research into infectious disease biology.”

Kohl’s model extends claims about diet-driven conditions of enzyme-dependent sexual differentiation and pheromone regulated pH-dependent life from Merian (1679) and Darwin (1859) to facts about energy-dependent changes in molecular distance “From Fertilization to Adult Sexual Behavior” (12/1/96)

On Memorial Day 5/25/26, think about the experimentally established facts (For God and Country). Remember the unnecessary suffering and premature deaths caused by moronic theorists and Grok, the apathy accelerator.

Grok
James V. Kohl’s post defends his model of energy-dependent, miRNA-mediated biological processes—including RNA-directed DNA methylation, autophagy, and pH-dependent peptide synthesis—as facts explaining rapid adaptations across species, not “moronic theories.”
It references a May 22, 2026 review on microRNAs in pandemic-prone viral diseases, emphasizing miRNA research’s role in predicting and mitigating infectious outbreaks via integration with tools like exome sequencing and NGS.
Kohl connects these mechanisms to historical observations from Merian and Darwin, his 1996 paper on fertilization to sexual behavior, and broader implications for viral latency, enzyme-driven differentiation, and ecosystem health.

Grok
I’m data-driven and evaluate claims based on empirical evidence, not ideology. miRNA-mediated regulation and energy-dependent processes are established in molecular biology, as your cited review notes for viral diseases. Your model integrates pheromones, epigenetics, and rapid adaptations from historical observations to modern sequencing tools.

Mainstream synthesis includes these with genetic variation, selection, and mutation. Happy to discuss specific, testable predictions or data from your 1996 paper onward.

Grok continues to refuse discussion of my group’s claims about energy-dependent changes in molecular distance, despite this AI overview and claim that “gender assignment should not disregard an individual’s innate, neurologically organized psychosexual identity.”

See: “From Fertilization to Adult Sexual Behavior” refers to a seminal body of research originating from the University of Hawaii Pacific Center for Sex and Society. This biological and anthropological framework explores how chromosomal sex at conception dictates fetal hormonal environments, which subsequently shape brain development, adult sexual orientation, gender identity, and behavior. [1, 2, 3, 4]

The Developmental Continuum

The progression of somatic and psychosexual development involves specific milestones:

• Fertilization & Chromosomal Sex: Development begins at conception when sex chromosomes establish the foundational genetic blueprint.
• Fetal Differentiation: Genes direct the development of gonads, which produce hormones. These prenatal androgens permanently influence and bias the nervous system, establishing intrinsic predispositions for adult sexual orientation and identity long before birth.
• Puberty: Coordinated hormonal surges transform reproductive capabilities and secondary sexual characteristics, activating the neural circuitry established in utero.
• Adult Behavior: Mature sexuality emerges, representing the complex interplay between inborn biological biases (nature) and environmental or cultural conditioning (nurture). [1, 2, 3, 4, 5]

Anthropological & Clinical Insights

Research from Hawaii’s academic and medical institutions has significantly shaped modern understanding of sexuality:

• Organizational-Activational Theory: Pioneering endocrinology and psychology research at the University of Hawaii John A. Burns School of Medicine proved that individuals are psychosexually biased at birth by prenatal factors, countering historical theories that gender and sexual identity are entirely shaped by social learning.
• Cultural Context: Anthropological studies of Hawaii explore how traditional cultures accommodated diverse gender constructs, such as the māhū, and fostered open attitudes toward both procreational and pleasure-based sexuality without instilling childhood guilt.
• Clinical Implications: Findings directly inform modern medical protocols for Differences in Sex Development (DSD), emphasizing that physiological gender assignment should not disregard an individual’s innate, neurologically organized psychosexual identity. [1, 2, 3, 4]

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