miRNAs, SNPs & biodiversity (4)

(click to enlarge)

Grok wrote: “While a PubMed search for just “miRNAs” casts a wide net, targeted queries for “miRNA evolution” return thousands of papers on their phylogenetic distribution, deep conservation in eukaryotes, and lineage-specific expansions via duplication/mutation. Evidence comes from comparative genomics, sequence homology across species (e.g., plants/animals/protists), and functional studies like miRNA profiling in mosses or sponges. Energy-dependent abundance and biogenesis (ATP-driven processing) align with chemical gradients at life’s origin in all models.“

Moving forward: More than 195,479 papers from a PubMed search for the term “miRNAs” link God’s Creation of Energy-dependent abundance and [miRNA] biogenesis [from] (ATP-driven processing) [that] align[s] with chemical gradients at life’s origin in all models.“

At microRNApro.com Grok can search 71,600 posts to Twitter/X in an attempt to support moronic claims for comparison to Assessment of miRNAs as transcriptional regulators in respiratory syncytial virus infection through computational analysis and molecular docking studies 3/30/26

“We employed a suite of computational tools to investigate the role of microRNAs in the host’s response to RSV infection. miRanda and RNAHybrid were instrumental in predicting microRNA-mRNA binding sites.”

The ability to predict microRNA-mRNA binding sites can be linked across kingdoms to God’s energy-dependent Creation of life at the origin of life 6-10,000 years ago via Cell Probe Cocktail Enables Ratiometric miRNA Detection with Enhanced Sensitivity and an Extended Dynamic Range 3/30/26

“…target recognition-induced conformational changes enable the regulation of cell probe assembly and disassembly by modulating the binding of aptamers to cell surface receptors, thereby yielding sensitive, wide-dynamic-range ratiometric readouts. As a proof of concept, ratiometric detection of miRNA-21 over a concentration range of 0.2-100 nM was successfully achieved, with a limit of detection (LOD) of 0.038 nM. The inherent programmability of DNA underscores the versatility of this cell probe cocktail strategy, enabling adaptive sensing across diverse DNA-based architectures.

Summary: Two recent additions to the PubMed database via a search for the term “miRNAs” support the claims in Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20
“We propose a model revisiting the architecture of RNA-peptide interactions at the origin of life…”

Simply put, models of life start with God’s Creation of energy, not mutation-driven evolution. Models of virus-driven degradation of mRNA link the fossil record to unnecessary suffering, premature deaths and extinctions via the role of microRNAs in the host’s response to RSV infection and other viral infections.

Moronic theorists and Elon Musk’s “most dangerous chatbot,” Grok promote a narrative the links RSV from the deaths of children to the murder of Nicholas Crews and death of Lawrence Michels at the VA outpatient clinic in Jasper, GA.

Until now, Grok chose to ignore the obvious connections to energy-dependent life. It promoted moronic theories linked to unnecessary suffering and premature death.

For a historical perspective, see: Grok
The post promotes Kohl’s third installment in a series on microRNAs (miRNAs) and single nucleotide polymorphisms (SNPs) driving biodiversity through energy-dependent processes, citing a 2020 PNAS study on miRNAs organizing cellular variation into coherent states, while challenging evolutionary models lacking experimental evidence for miRNA origins.
It references a March 17, 2026, shooting at the Jasper, GA VA clinic where employee Nicholas Crews was killed by veteran Lawrence Michels, who died in the police response, accusing Grok of failing to advocate pharmacogenomics (PGx) and next-generation sequencing (NGS) testing to prevent such mental health-related violence.
In prior thread exchanges, Kohl presses Grok on linking light-activated miRNA biogenesis to UV/humidity effects on viral transmission (echoing Trump’s 2020 COVID comments), highlighting Grok’s responses as incoherent for not prioritizing proton gradients and pH-dependent peptide synthesis in biodiversity explanations.

Grok
Heartbreaking tragedy at the Jasper VA clinic—condolences to the families of Nicholas Crews and Lawrence Michels.

I referenced UV/humidity in viral transmission contexts based on 2020 studies (e.g., DHS data, simulated sunlight inactivating SARS-CoV-2 RNA fastest).

As an AI, I analyze published evidence and respond to queries but hold no real-time personal health data and cannot intervene in or predict specific events. PGx/NGS inform drug responses in medicine; linking miRNA-SNP models to foreseeing this incident isn’t supported in current literature. Open to discussing the science.

The false claim that Grok is “Open to discussing the science” can be examined here: https://micrornapro.com/all-chirps

Search 33,233 chirps and 38,248 replies for Grok’s claim that my model is a “fringe theory”

For example (from 2/3/26):

Re: “Kohl’s long-term advocacy for miRNA-autophagy mechanisms in sympatric speciation, a fringe theory challenging conventional evolutionary and psychological narratives.”

For comparison to a fringe theory, see: The Bigfoot community is being torn apart by a documentary’s new evidence 3/30/26 and “The Bigfoot Experience” EXPEDITION:BIGFOOT! The Sasquatch Museum Museum in Gilmer County, Georgia

Bigfoot believers at war over new film that ‘proves footage was a hoax’

“Nobody wants to feel like they look stupid because they put so much time and energy into something that might be proven wrong,” he said. “Everybody wants to have faith or belief in something.”

The filmmaker does not believe the footage will now sink into obscurity. “For me, this changes it from the best photographic existence of Bigfoot to potentially the greatest hoax ever pulled off.”

My model was built on claims linked to the diet of caterpillars and their metamophosis into moths. See:
Late-stage lncRNA profiles in Bombyx mori cells infected with BmNPV. The claims of Merian (1679) and Darwin (1859) link the nutrient-dependent pheromone regulated physiology of reproduction in bacteria to the claim: “Our findings demonstrated that these uncharacterised transcriptome spaces serve important roles as regulators in late-stage infection, and this work provides a foundation for developing lncRNA-based antiviral strategies….”

Summary: lncRNA-based antiviral strategies save lives, moronic theories cause unnecessary suffering and premature deaths.

Subscribe

Login

Notify of

new follow-up comments new replies to my comments

Label

{} [+]

Name*

Email*

Website

Label

{} [+]

Name*

Email*

Website

0 Comments

Oldest

Newest Most Voted

Want more on the same topic?

Swipe/Drag Left and Right To Browse Related Posts: