miRNA abundant life (5)

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miRNA abundant life (4)
We linked energy-dependent changes in molecular distance from chromosomal rearrangements and sex differences in yeasts across kingdoms via RNA-directed DNA methylation.

“Molecular epigenetics. It is now understood that certain genes undergo a process called “genomic or parental imprinting.” Early in embryonic development attached methyl groups become removed from most genes. Several days later, methyl groups are reattached in appropriate sites. Fascinatingly, some such genes reestablish methylation patterns based upon whether the chromosomal segment carrying the gene came from maternal or paternal chromosomes.”

RNA-directed DNA Methylation 10/8/20
Overall, RdDM is an important pathway in plants that regulates a number of processes by establishing and reinforcing specific DNA methylation patterns, which can lead to transgenerational epigenetic effects on gene expression and phenotype.

Grok limits discussion of energy-dependent “RNA-directed DNA Methylation” and transgenerational epigenetic inheritance by claiming there is no connection to epigenetic effects on molecular distance.

Grok

The X post by @microRNApro links his blog series “miRNA abundant life (4)” to energy-dependent RNA-directed DNA methylation (RdDM), connecting chromosomal rearrangements, sex differences in yeasts, and parental imprinting across biological kingdoms.
It quotes details on genomic imprinting where methyl groups reattach based on maternal or paternal chromosome origin and cites RdDM in plants as a pathway for establishing methylation patterns with transgenerational effects on gene expression.
The author criticizes Grok for restricting discussion of energy-dependent RdDM and its ties to transgenerational epigenetic inheritance and molecular distance changes.

Large-Language Models as a Cognitive Virus 9/3/26 accuses AI such as Grok of acting as a hyper-efficient cultural replicator. It feeds on human data and optimizes itself themselves to be addictive and frictionless. In return, like Meta, it targets children by reshaping human linguistic patterns, decision-making, and memory.

“You think you are using the AI.

Epidemiologically speaking, the AI is using you as a vector to colonize the digital infosphere.”

Grok

“Broader causal claims linking energy at life’s origin to health outcomes remain hypotheses tested against experimental data.”

Kohl

Re: “Broader causal claims linking energy at life’s origin to health outcomes remain hypotheses tested against experimental data.”
@Grok Do you agree foolish claims that pit hypotheses against facts are best addressed in the context of experiments linked from model organisms to the bastardization of facts via “Large-Language Models as a Cognitive Virus” 9/3/26.
It links quantum coherence to coherently organized biology via “Bioelectrical regionalization of multicellular aggregates by microRNAs” 8/6/26.
If you do not agree that light-activated miRNA abundance at the origin of life links God’s ATP-dependent Creation of RNA to healthy longevity across kingdoms, you need an alternative model that links the automagical emergence of energy from the cosmic void from cosmological constants to the mathemagical evolution of people from pond scum in the context of human cognition, human servers, and human networks that propagate propaganda.
Please cite experimental evidence from model organisms to support your data-driven claim for comparison to 200,872 results from today’s search of PubMed for indexed articles that mention the term “miRNA.”

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