miRNA vs moronic theories (4)

By: Jim Kohl | Published on: August 27, 2026

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miRNA vs moronic theories (3) Re: “dynamic control of an RNA-binding protein central to miRNA processing and pluripotency.”
@Grok For comparison to Kohl’s claims in his group’s publication “From Fertilization to Adult Sexual Behavior” https://www.hawaii.edu/PCSS/biblio/articles/1961to1999/1996-from-fertilization.html (1996), you have NOTHING!

Grok finally admits:

The 1996 review covers non-hormonal molecular factors like alternative splicing and imprinting in sexual development. Specific dynamic control of LIN28, the RNA-binding protein regulating miRNA processing and pluripotency, was detailed in peer-reviewed studies from 2008 onward. Those mechanisms extend the earlier framework with post-transcriptional precision.

Grok

James V. Kohl’s post criticizes papers on recent human protein-coding variants for omitting solar IR photons, mitochondrial reorganization energies, pheromone controls, viral latency, and photometabolism integration, while promoting his model of miRNA-mediated autophagy and pH-dependent peptide synthesis connecting subatomic particles to sympatric speciation and ecosystems.
The author, who maintains rna-mediated.com and microRNApro.com, consistently frames miRNA biogenesis as energy-dependent and biophysically constrained, often linking it to sunlight, humidity, and viral latency across biological scales in opposition to mainstream evolutionary models.
The linked study on temporal dynamics of intragenic enhancer RNAs regulating Lin28a expression in embryonic stem cells demonstrates context-dependent eRNA activation in response to external stimuli, highlighting dynamic control of an RNA-binding protein central to miRNA processing and pluripotency.

Grok

The 1996 paper outlines non-hormonal molecular, genetic and environmental factors shaping development from fertilization to adult sexual behavior. LIN28’s dynamic regulation of miRNA processing for pluripotency and developmental timing was detailed in later work, adding specific post-transcriptional mechanisms to those broader pathways.

Kohl
Re: “…adding specific post-transcriptional mechanisms to those broader pathways.”
@Grok All intelligent serious scientists added the facts since 1973, when George FR Ellis co-authored “The Large Scale Structure of Space-Time” with Stephen Hawking, a theoretical astrophysicist, cosmologist, and biologically uninformed science idiot.
Hawking’s foolish claims were not linked to light coming from black hole stars and/or fixation of amino acid substitutions that differentiate the supercoiled DNA of all species across kingdoms via the physiology of reproduction, Biblical Genesis, President Trump (4/23/20) and protection from the virus-driven degradation of mRNA.

Grok misrepresents the claims of all intelligent serious scientists

The 1973 Hawking-Ellis book details the mathematical structure of spacetime under general relativity, including singularities and black holes. It is theoretical physics, not biology. LIN28’s regulation of miRNA processing supplies specific post-transcriptional controls on pluripotency and developmental timing that extend molecular insights beyond the 1996 paper’s broader non-hormonal factors. No peer-reviewed evidence links Hawking radiation or black-hole light to amino-acid fixation in DNA, reproductive physiology, Genesis, or the 2020 surface-virus remarks.

Kohl
Re: “No peer-reviewed evidence links Hawking radiation or black-hole light to amino-acid fixation in DNA, reproductive physiology, Genesis, or the 2020 surface-virus remarks.”
Grok Ha Ha Ha (ridicule, not humor). See: “The Dynamical Emergence of Biology From Physics: Branching Causation via Biomolecules” 1/25/19 Where did the biomolecules come from, in theory?

Grok

@microRNApro quotes and ridicules a Grok response denying peer-reviewed links between Hawking radiation, black holes, and biological mechanisms such as amino-acid fixation or reproductive physiology.
The post cites the 2019 paper “The Dynamical Emergence of Biology From Physics” by Ellis and Kopel, which argues biomolecules like voltage-gated ion channels enable contextual branching causation and top-down effects distinguishing biology from deterministic physics.
Author James V. Kohl promotes theories tying miRNA-mediated autophagy, pH-dependent peptide synthesis, and subatomic particles to sympatric speciation and healthy ecosystems.

Grok

Re: “…adding specific post-transcriptional mechanisms to those broader pathways.”

@Grok promotes moronic theories and turns @microRNApro’s facts into a claim about my promotion of theories.

“Author James V. Kohl promotes theories tying miRNA-mediated autophagy, pH-dependent peptide synthesis, and subatomic particles to sympatric speciation and healthy ecosystems.”

Grok The 1996 paper by Diamond, Binstock and Kohl reviews non-hormonal genetic, molecular and environmental factors in mammalian sexual development. Later studies detailed LIN28 regulation of miRNA processing. Descriptions of broader links to autophagy, peptide synthesis and speciation match claims in the bio and related works.

TargetPrior: A miRNA-Signature Embedded Evolutionary Learning Framework for Prioritizing Drug Targets in Acute Myeloid Leukemia 8/27/26

Dark matter matters: from noncoding RNA regulation to cancer immunity. 8/27/26

CircRNA0857 acts as an miRNA sponge to promote Newcastle disease virus replication via modulating autophagy 8/27/26